Comparison of presepsin and Mid-regional pro-adrenomedullin in the diagnosis of sepsis or septic shock: a systematic review and meta-analysis
Jun Liang1, Yingli Cai1 and Yiming Shao2*
*Correspondence:
Yiming Shao
zqyylj@163.com
1 Department of Emergency, the First People’s Hospital of Zhaoqing, Zhaoqing City, China
2 Jinan University, No.601, West Huangpu Avenue, Guangzhou 510632, China
Perinatal presepsin assessment: a new sepsis diagnostic tool?
*Corresponding author: Prof. Diego Gazzolo, Neonatal Intensive Care Unit, G. D’Annunzio University, 65100 Chieti, Italy, Phone: +39 0871 358219, E-mail: dgazzolo@hotmail.comValentina Botondi, Ebe D’Adamo, Marika Perrotta, Laura Di Ricco, Cynzia Spagnuolo, Sara De Sanctis, Elisabetta Barbante and Gabriella Levantini, Neonatal Intensive Care Unit, G. D’Annunzio University, Chieti, Italy
Mario Plebani, Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy. https://orcid.org/0000-0002-0270-1711
Oriana Trubiani, Department of Innovative Technologies in Medicine & Dentistry, University “G. D’Annunzio”, Chieti, Italy
Maria Chiara Strozzi, Antonio Maconi, Marta Betti and Annalisa Roveta, AO SS Antonio, Biagio and C. Arrigo Hospital, Alessandria, Italy. https://orcid.org/0000-0002-1904-7277 (A. Roveta) Francesca Gazzolo, Magna Graecia University, Catanzaro, Italy
Evaluation of presepsin as a diagnostic tool in newborns with risk of early-onset neonatal sepsis
Iva Pospisilova1,2, Helena L. Brodska3, Marketa Bloomfield2,4, Klara Borecka1 and Jan Janota5,6,7*1Department of Clinical Chemistry, First Faculty of Medicine, Thomayer University Hospital and Charles University, Prague, Czech Republic
2Department of Pediatrics, First Faculty of Medicine, Thomayer University Hospital and Charles University, Prague, Czech Republic
3The Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, General University Hospital and Charles University, Prague, Czech Republic
4Department of Immunology, Second Faculty of Medicine, Motol University Hospital and Charles University, Prague, Czech Republic
5Department of Obstetrics and Gynecology, Neonatal unit, Second Faculty of Medicine, Motol University Hospital and Charles University, Prague, Czech Republic
6Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
7Department of Neonatology, First Faculty of Medicine, Thomayer University Hospital and Charles University, Prague, Czech Republic
Presepsin as a Diagnostic and Prognostic Biomarker in Sepsis
Использование комбинации биомаркеров для ранней диагностики сепсиса у пациентов отделения реанимации и интенсивной терапии
М.Г. Вершинина 1, 2*, Н.И. Стериополо 1, А.М. Иванов 3, М.Е. Малышев 41 ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами
Президента РФ, Москва
2 ФГАУ «НМИЦ здоровья детей» Министерства здравоохранения РФ, Москва
3 ФГБВОУ ВО ВМедА им. С.М. Кирова, Санкт-Петербург
4 ГБУ СПб НИИ скорой помощи им. И.И. Джанелидзе, Санкт-Петербург
Ранние лабораторные маркеры неонатального сепсиса — действительно ли они помогают врачу спасти жизнь?
А. Н. Обедин1, 2, А. Ю. Васильев2, Н. В. Зубенко21 Ставропольский государственный медицинский университет, Российская Федерация
2 Краевой клинический перинатальный центр No 1, Ставрополь, Российская Федерация
Пресепсин как маркер сепсиса у онкологических больных после хирургических вмешательств
Н. К. Гуськова1, А. А. Морозова1, Д. А. Розенко1, А. В. Алешкина1, А. М. Скопинцев1, О. Н. Селютина1, Н. В. Голомеева1, Е. А. Гуськова2, А. К. Донская1, И. В. Целищева1, А. С. Ноздричева11. НМИЦ онкологии, г. Ростов-на-Дону, Российская Федерация
2. Клинико-диагностический центр «ДА ВИНЧИ», г. Ростов-на-Дону, Российская Федерация
Email: guskova.nailya@mail.ru
Diagnostic Evaluation of Hematological Sepsis Score and Presepsin in Neonatal Sepsis
Marina Mamdouh Malky Ibrahim1, Dalia Ahmed El-Sewefy1, Mariam John Amin Ibrahim1, Shaimaa Abdelmalik Pessar1,*1 Faculty of Medicine — Ain Shams University, Cairo, Egypt
*Corresponding Author: Dr Shaimaa Abdelmalik Pessar, Faculty of Medicine, Ain Shams University, Abbasseya, Cairo, Egypt.
Email: shaimaamalik@med.asu.edu.eg
Diagnostic value of presepsin in odontogenic infection: a retrospective study
Eun‐Sung Kang and Jae‐Hoon Lee**Correspondence: lee201@dankook.ac.kr
Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University, 119 Dandae‐ro, Cheonan, Chungcheongnam‐do 31116, Republic of Korea
Пресепсин для диагностики раннего неонатального сепсиса: систематический обзор и мета-анализ
Poggi C, Lucenteforte E, Petri D, De Masi S, Dani C.Presepsin for the Diagnosis of Neonatal Early-Onset Sepsis: A Systematic Review and Meta-analysis. JAMA Pediatr. 2022 May 31. doi: 10.1001/jamapediatrics.2022.1647
Presepsin: Hope in the Quest for the Holy Grail
Abhishek Samprathi1, Madhusudan Samprathi2, Mounika Reddy31 Department of Critical Care Medicine, Fortis Hospitals, Bengaluru, Karnataka, India
2,3 Department of Pediatrics, All India Institute of Medical Sciences, Hyderabad, Telangana, India
Corresponding Author: Madhusudan Samprathi, Department of Pediatrics, All India Institute of Medical Sciences, Hyderabad, Telangana, India, Phone: +917077703235, e-mail: madhu_1511@yahoo.com
Современные маркеры воспалительного процесса в хирургической практике
А.М. Морозов, https://orcid.org/0000-0003-4213-5379, ammorozovv@gmail.comА.Н. Сергеев, https://orcid.org/0000-0002-9657-8063
С.В. Жуков, https://orcid.org/0000-0002-3145-9776
Н.С. Новикова, https://orcid.org/0000-0003-4564-4777
М.А. Беляк, https://orcid.org/0000-0001-6125-7676
Тверской государственный медицинский университет; 170100, Россия, Тверь, ул. Советская, д. 4
Perinatal presepsin assessment: a new sepsis diagnostic tool?
Valentina Botondi, Ebe D’Adamo, Mario Plebani, Oriana Trubiani, Marika Perrotta, Laura Di Ricco, Cynzia Spagnuolo, Sara De Sanctis, Elisabetta Barbante, Maria Chiara Strozzi, Antonio Maconi, Francesca Gazzolo, Marta Betti, Annalisa Roveta, Gabriella Levantini and Diego Gazzolo*Valentina Botondi, Ebe D’Adamo, Marika Perrotta, Laura Di Ricco, Cynzia Spagnuolo, Sara De Sanctis, Elisabetta Barbante and Gabriella Levantini, Neonatal Intensive Care Unit, G. D’Annunzio University, Chieti, Italy
Mario Plebani, Department of Laboratory Medicine, University Hospital of Padova, Padova, Italy. https://orcid.org/0000-0002-0270-1711
Oriana Trubiani, Department of Innovative Technologies in Medicine & Dentistry, University “G. D’Annunzio”, Chieti, Italy
Maria Chiara Strozzi, Antonio Maconi, Marta Betti and Annalisa Roveta, AO SS Antonio, Biagio and C. Arrigo Hospital, Alessandria, Italy. https://orcid.org/0000-0002-1904-7277 (A. Roveta)
Francesca Gazzolo, Magna Graecia University, Catanzaro, Italy
*Corresponding author: Prof. Diego Gazzolo, Neonatal Intensive Care Unit, G. D’Annunzio University, 65100 Chieti, Italy, Phone: +39 0871 358219, E-mail: dgazzolo@hotmail.com
Концентрация липополисахарид-связывающего белка и пресепсина у пациентов с вирусным поражением легких SARS-CoV-2, проживающих в Республике Крым
И.А. Яцков1, В.А. Белоглазов1, А.В. Кубышкин1, А.П.Николаева1, Е.Ю. Зяблицкая1, Ю.Е. Куницкая1, Э.Н. Лавренчук21 Медицинская академия имени С.И.Георгиевского Федерального государственного автономного образовательного учреждения высшего образования «Крымский федеральный университет имени В.И.Вернадского» Министерства науки и высшего образования Российской Федерации: 295007, Россия, Республика Крым, Симферополь, просп. Академика Вернадского, 4
2 Государственное бюджетное учреждение здравоохранения Республики Крым «Республиканская клиническая больница имени Н.А.Семашко»: 295017, Россия, Республика Крым, Симферополь, ул. Киевская, 69
Пресепсин в диагностике нозокомиальной инфекции центральной нервной системы
С.А. Абудеев1, К.В. Киселев2, О.В. Паринов1, Ю.Д. Удалов1, М.В. Забелин1, А.С. Самойлов1, К.А. Попугаев1*Отделение нейрореанимации и нейроанестезиологии
1 ФГБУ «ГНЦ — ФМБЦ имени А.И. Бурназяна» ФМБА,
Российская Федерация, 123098 Москва, ул. Маршала Новикова, д. 23
2 ГБОУ ВО «РНИМУ имени Н.И. Пирогова» Минздрава России, Российская Федерация, 117997 Москва, ул. Островитянова, д. 1
* Контактная информация: Попугаев Константин Александрович, доктор медицинских наук, заведующий отделением нейрореанимации ФГБУ ГНЦ ФМБЦ А.И. Бурназяна ФМБА России. E-mail: stan.popugaev@yahoo.com
Biomarkers of Neonatal Sepsis: From Being Mere Numbers to Becoming Guiding Diagnostics
Sai Sravya Gude 1, Nikhil Chowdary Peddi 2, Sravya Vuppalapati 2, Shravya Venu Gopal 3, Harshita Marasandra Ramesh 4, Sai Sreeya Gude 51 Pediatrics, Guntur Medical College, Guntur, IND
2 Pediatrics, PES Institute of Medical Sciences and Research, Kuppam,IND
3 InternalMedicine,KasturbaMedicalCollegeMangalore,Mangalore,IND
4 InternalMedicineand Pediatrics, Kasturba Medical College Mangalore, Mangalore, IND
5 Internal Medicine, Guntur Medical College, Guntur, IND
Corresponding author: Nikhil Chowdary Peddi, nikhilchowdarypeddi@gmail.com
Диагностическое значение пресепсина как маркера врожденного инфекционного процесса у новорожденных детей
Д.Р. Шарафутдинова1, 2, Е.Н. Балашова1, Ю.В. Сухова1, Ю.В. Кесслер1, А.Р. Киртбая1, 2, А.Ю. Рындин1, 2, Ю.М. Голубцова1, 2, И.А. Шакин1, А.В. Соломонова3, Е.И. Артамкина2, Т.Ю. Иванец1, О.В. Ионов1, 2, В.В. Зубков1, 21 ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова» Минздрава России, Москва
2 ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет), Москва
3 ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва
Combined Use of Presepsin and (1,3)-β-D-glucan as Biomarkers for Diagnosing Candida Sepsis and Monitoring the Effectiveness of Treatment in Critically Ill Patients
Radim Dobiáš 1,2,†, Marcela Kánová 3,4,5,*,†, Nadežda Petejová 6,7,8, Štefan Kis Pisti 9, Robert Bocek 10, Eva Krejcí 1,2, Helena Stružková 2, Michaela Cachová 1, Hana Tomášková 11,12, Petr Hamal 13, Vladimír Havlícek 14,15,† and Milan Raška 16,†.1 Department of Bacteriology and Mycology, Public Health Institute in Ostrava, 702 00 Ostrava, Czech Republic; radim.dobias@zuova.cz (R.D.); eva.krejci@zuova.cz (E.K.); michaela.cachova@zuova.cz (M.C.)
2 Institute of Laboratory Medicine, Faculty of Medicine, University of Ostrava, 703 00 Ostrava, Czech Republic; helcastruzkova@seznam.cz
3 Department of Anesthesiology and Intensive Care Medicine, University Hospital Ostrava, 708 00 Ostrava, Czech Republic
4 Institute of Physiology and Pathophysiology, Faculty of Medicine, University of Ostrava, 710 00 Ostrava, Czech Republic
5 6 Department of Internal Medicine, University Hospital Ostrava, 708 00 Ostrava, Czech Republic; petejova@seznam.cz
7 Department of Internal Medicine, University of Ostrava, 703 00 Ostrava, Czech Republic
8 Department of Internal Medicine III—Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacký University Olomouc, 775 15 Olomouc, Czech Republic
9 Department of Anesthesiology and Resuscitation, Ostrava City Hospital, 728 80 Ostrava, Czech Republic
10 Department of Anesthesiology and Resuscitation, Hospital with Polyclinic Havířov, 736 01 Havířov, Czech Republic
11 Center of Health Services, Institute of Public Health in Ostrava, 702 00 Ostrava, Czech Republic
12 Department of Epidemiology and Public Health, Faculty of Medicine, University of Ostrava, 703 00 Ostrava, Czech Republic
13 Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University Olomouc, 775 15 Olomouc, Czech Republic
14 Institute of Microbiology of the Czech Academy of Sciences, 142 20 Prague, Czech Republic
15 Department of Analytical Chemistry, Faculty of Science, Palacký University, 771 46 Olomouc, Czech Republic
16 Department of Immunology, Faculty of Medicine and Dentistry, Palacký University Olomouc, 775 15 Olomouc, Czech Republic
* Correspondence: marcela.kanova@fno.cz
† These authors contributed equally to this work.
Usefulness of presepsin for the early detection of infectious complications after elective colorectal surgery, compared with C‐reactive protein and procalcitonin
Erika Amanai1, Kishiko Nakai1*, Junichi Saito2, Eiji Hashiba2, Takuya Miura3, Hajime Morohashi3, Yoshiyuki Sakamoto3, Akio Mikami4, Kenichi Hakamada3 & Kazuyoshi Hirota51 Department of Anesthesiology, Hirosaki University Hospital, 5 Zaifu-cho, Hirosaki, Aomori 036-8562, Japan.
2 Division of Intensive Care Unit, Hirosaki University Hospital, Hirosaki, Japan.
3 Department of Gastroenterological Surgery and Pediatric Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
4 Central Clinical Laboratory, Hirosaki University Hospital, Hirosaki, Japan.
5 Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
* Email: kishiko_sk1064@hirosaki-u.ac.jp
Antimicrobial Stewardship Using Biomarkers: Accumulating Evidence for the Critically Ill
Evdoxia Kyriazopoulou 1 and Evangelos J. Giamarellos-Bourboulis 2,*1 2nd Department of Critical Care Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece; ekyri@med.uoa.gr
2 4th Department of Internal Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece
* Correspondence: egiamarel@med.uoa.gr; Tel.: +30-210-5831994
A simple prognostic score based on troponin and presepsin for COVID-19 patients admitted to the emergency department: a single-center pilot study
Paola Dell’Aquila1; Pasquale Raimondo2; Daniele Orso3; Paola De Luca1; Pietro Pozzessere1; Carmen Vita Parisi1; Tiziana Bove3; Luigi Vetrugno3; Salvatore Grasso2; Vito Procacci1.1 Department of Emergency Medicine, University Hospital of Bari, Bari, Italy;
2 Department of Emergency and Organ Transplant, University of Bari Aldo Moro, Bari, Italy;
3 Department of Medicine, University of Udine, Udine, Italy & Department of Anesthesia and Intensive Care Medicine, ASUFC Hospital of Udine, Udine, Italy.
Presepsin value predicts the risk of developing severe/critical COVID-19 illness: results of a pooled analysis
Giuseppe Lippi*, Fabian Sanchis-Gomar and Brandon M. Henry*Corresponding author: Prof. Giuseppe Lippi, Section of Clinical Biochemistry, University Hospital of Verona, Piazzale L.A. Scuro, 10, 37134 Verona, Italy, Phone: 0039 045 8122970, Fax: 0039 045 8124308, E-mail: giuseppe.lippi@univr.it. https://orcid.org/0000- 0001-9523-9054
Fabian Sanchis-Gomar, Department of Physiology, Faculty of Medicine, University of Valencia and INCLIVA Biomedical Research Institute, Valencia, Spain
Brandon M. Henry, Cardiac Intensive Care Unit, The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
Type 1 inflammatory endotype relates to low compliance, lung fibrosis, and severe complications in COVID-19
Takehiro Hasegawaa, *, Atsushi Nakagawab, Kohjin Suzukic, Kazuto Yamashitad, Saya Yamashitae, Niina Iwanagad, Eiya Tamadad, Kenta Nodad, Keisuke Tomiiba Sysmex R&D Centre Europe GmbH, Research and Development Division, Falkenried 88, 20251 Hamburg, Germany b Kobe City Medical Centre General Hospital, 2-1-1, Minamimachi, Minatojima, Chuo Ward, Kobe, Japan
c Sysmex System Technology Laboratories, 4-4-4, Takatsuka-dai, Nish Ward, Kobe, Japan
d Sysmex Central Research Laboratories, 4-4-4, Takatsuka-dai, Nish Ward, Kobe, Japan
e Sysmex Business Incubation Department, 4-4-4, Takatsuka-dai, Nish Ward, Kobe, Japan
Presepsin as a Novel Biomarker in predicting Inhospital Mortality in COVID-19 Pneumonia Patients
Hebatallah Hany Assal*, MD., Hebatallah.Assal@kasralainy.edu.eg, Safaa Abdelrahman, MD., safaa.mohamed5@gmail.com, Maha AlyAlden Abdelbasset, MD., maha.aly@gmail.com, Mai Abdelaziz, MD., maiabdelaziz1979@gmail.com, Irene Mohamed Sabry*, MD., irene.sabry@yahoo.com, Marwa Moawad Shaban*, MD., marwamoawad@ymail.comCorrespondence:
Hebatallah Hany Assal, MD, Hebatallah.Assal@kasralainy.edu.eg, Tel: 01223939861
Address: Department of Chest Medicine, Faculty of Medicine, Cairo University, Al Kasr Al Aini, Old Cairo Cairo,11956, Egypt
Биомаркеры инфекции в оптимизации антибактериальной терапии: оправданные ожидания
Кулабухов В.В.1, Шабанов А.К.1, Андреева И.В.2, Стецюк О.У.2, Андреев В.А.31 НИИ скорой помощи им. Н.В. Склифосовского, Москва, Россия
2 НИИ антимикробной химиотерапии ФГБОУ ВО СГМУ Минздрава России, Смоленск, Россия
3 ФГБОУ ВО «Смоленский государственный медицинский университет» Минздрава России, Смоленск, Россия
Контактный адрес: Ирина Вениаминовна Андреева, E-mail: Irina.Andreeva@antibiotic.ru
Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019
F. Linzee Mabrey, MD1, Eric D. Morrell, MD1, Pavan K. Bhatraju, MD, MSc1, Neha A. Sathe, MD1, Sana S. Sakr, PhD1, Sharon K. Sahi, BS1, T. Eoin West, MD, MPH1, Carmen Mikacenic, MD2, Mark M. Wurfel, MD, PhD1Prediction of Postoperative Sepsis Based on Changes in Presepsin Levels of Critically Ill Patients with Acute Kidney Injury after Abdominal Surgery
Chang Hwan Kim and Eun Young Kim *Division of Trauma and Surgical Critical Care, Department of Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea;
changhwan.kim0227@gmail.com *
Correspondence: freesshs@naver.com;
The Emerging Role of Presepsin (P-SEP) in the Diagnosis of Sepsis in the Critically Ill Infant: A Literature Review
Chiara Maddaloni 1, Domenico Umberto De Rose 1 , Alessandra Santisi 1, Ludovica Martini 1, Stefano Caoci 1, Iliana Bersani 1, Maria Paola Ronchetti 1,2 and Cinzia Auriti 1,*,†1 Neonatal Intensive Care Unit (NICU), Medical and Surgical Department of the Fetus—Newborn-Infant, “Bambino Gesù” Children’s Hospital IRCCS, 00165 Rome, Italy; chiara.maddaloni@opbg.net (C.M.); domenico.derose@opbg.net (D.U.D.R.); alessandra.santisi@opbg.net (A.S.); ludovica.martini@opbg.net (L.M.); stefano.caoci@opbg.net (S.C.); iliana.bersani@opbg.net (I.B.); mariapaola.ronchetti@opbg.net (M.P.R.)
2 Neonatal Intensive Care (NICU) and Neonatal Pathology, San Vincenzo Hospital, 98039 Taormina, Italy
Correspondence: cinzia.auriti@opbg.net; Tel.: +39-06-6859-2427; Fax: +39-06-6859-3916
† On behalf of the Study Group of Neonatal Infectious Diseases of the Italian Society of Neonatology (SIN)
Presepsin as a predictor of septic shock in patients with urinary tract infection
Yoshitaka Sekine1*, Kazuhiko Kotani2, Daisuke Oka1, Hiroshi Nakayama1 et al.1 Department of Urology, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi 371-8511, Japan
2 Division of Community and Family Medicine, Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke, Japan.
3 Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
*Correspondence: ysekine@gunma-u.ac.jp
Perioperative presepsin as a potential early predictor for postoperative infectious complications in cardiac surgery
Hiroto Suzuki1, Hiroto Narimatsu2, Masaki Nakane3, Mitsuaki Sadahiro4, Kaneyuki Kawamae11 Department of Anaesthesiology, Yamagata University Faculty of Medicine, Yamagata, Japan
2 Cancer Prevention and Cancer Control Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan 3Department of Emergency and Critical Care Medicine, Yamagata University Faculty of Medicine, Yamagata, Japan
4 Department of Cardiovascular, Thoracic and Pediatric Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan
Serum level of soluble CD14 subtype predicts long-term prognosis in sepsis patients with cardiac dysfunction
Junliang Liu1, Mingying Dai2, Hongyun Yang3, Lei Song1, Kun Chen4 et al.1 ICU, Renmin Hospital of Chengyang District, Qingdao, China; 2ICU, Affiliated Hospital of Qingdao University, Qingdao, China; 3ICU, General Hospital of Eastern Theater, Nanjing, China; 4ICU, Guannan Division, The First Renmin Hospital, Lianyungang, China
Contributions: (I) Conception and design: J Liu; (II) Administrative support: M Dai; (III) Provision of study materials or patients: H Yang, L Song; (IV) Collection and assembly of data: K Chen, Y Wang; (V)
Data analysis and interpretation: J Liu, M Hua; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.
Correspondence to: Ming Hua. ICU, Guannan Division, The First Renmin Hospital, Lianyungang 222042, China. Email: hm2000lyg@163.com
Presepsin as Early Marker of Sepsis in Emergency Department: A Narrative Review
Andrea Piccioni1, Michele Cosimo Santoro1,*, Tommaso de Cunzo2 et al.1 Emergency Medicine Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy;
andrea.piccioni@policlinicogemelli.it (A.P.); sara.cicchinelli@policlinicogemelli.it (S.C.); marcomaria.pascale@policlinicogemelli.it (M.M.P.); marcello.candelli@policlinicogemelli.it (M.C.); marcello.covino@policlinicogemelli.it (M.C.); francesco.franceschi@policlinicogemelli.it (F.F.)
2 Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy;
tomdecunzo@gmail.com (T.d.C.); gianlucatullo@gmail.com (G.T.); saviange@libero.it (A.S.); fede.valletta@gemelli.com (F.V.)
* Correspondence: michelecosimo.santoro@policlinicogemelli.it
Presepsin and Procalcitonin as Potential Biomarkers for Early Diagnosis and Prognosis of Sepsis in Critically Ill Patients
Reham Sabry 1, Hend Maghraby Maghraby 2*, Amany Mohamed Abd Allah 21 Clinical Pathology Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
2 Internal Medicine Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt
Email: *drhendms@gmail.com
Role of Plasma Presepsin, Procalcitonin and C-reactive Protein Levels in Determining the Severity and Mortality of Community-Acquired Pneumonia in the Emergency Department
Izzettin Hur1, Seda Ozkan2;*, Ali Halici3, Kerim Abatay4, Eren Usul5, Esra Cetin6, Fevzi Nuri Aydin61 Department of Emergency Medicine, Ministry of Health Pursaklar State Hospital, Ankara, Turkey
2 Department of Emergency Medicine, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey
3 Department of Emergency Medicine, Ministry of Health Polatlı State Hospital, Ankara, Turkey
4 Department of Emergency Medicine, Ministry of Health Muş State Hospital, Muş, Turkey
5 Department of Emergency Medicine, Ministry of Health Dr. Nafiz Korez Sincan State Hospital, Ankara, Turkey
6 Department of Clinical Biochemistry, Diskapi Yildirim Beyazit Training & Research Hospital, Ankara, Turkey
Correspondence: sedacil@gmail.com (Seda Ozkan)
The Effect Of Soluble CD14 Subtype (sCD14ST)/Presepsin And Lactate Clearance On Mortality Status In Pneumonia Patients With Sepsis
Zikanovelia1, Ngakan Putu Parsama Putra1, Yani Jane Sugiri1, Harun Al Rasyid21 Department of Pulmonology and Respiration Medicine, Faculty of Medicine, Universitas Brawijaya/ RSUD Dr. Saiful Anwar, Malang
2 Department of Department of Public Health Sciences and Preventive Medicine, Faculty of Medicine, Universitas Brawijaya/RSUD Dr. Saiful Anwar, Malang
Correspondence: Zikanovelia - zikanovelia@gmail.com
Presepsin as a Predictive Biomarker of Severity in COVID-19: A Systematic Review
Sibtain Ahmed1, Maheen Mansoor2, Muhammad S Shaikh3, Imran Siddiqui41,3,4 Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan
2 Department of Medical College, Aga Khan University, Karachi, Pakistan
Corresponding Author: Sibtain Ahmed, Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan, e-mail: sibtain.ahmed@aku.edu
Role of presepsin compared to C-reactive protein in sepsis diagnosis and prognostication
Mohamed El-Saied El-Shafiea, Khaled M. Taemaa,❋, Moataz M. El-Hallaga, Abdallah Mohamed Abdallah KandeelbaCritical Care Medicine, Cairo University, Egypt
bCritical Care Medicine, El-Sahel Teaching Hospital, Egypt
Complementary Use of Presepsin with the Sepsis-3 Criteria Improved Identification of High-Risk Patients with Suspected Sepsis
Jong Eun Park1,2,†, Beomki Lee3,†, Sun Joo Yoon4, Chi-Min Park5,6, Chul Won Jung7, Myung-Ju Ahn7,Hyung-Doo Park3, Sung Yeon Hwang1, Tae Gun Shin1,* and Eun-Suk Kang3,*
1 Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of
Medicine, Seoul 06351, Korea; jongeun7.park@samsung.com (J.E.P.); sygood.hwang@samsung.com (S.Y.H.)
2 Department of Emergency Medicine, College of Medicine, Kangwon National University,
Chuncheon 24289, Korea
3 Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University
School of Medicine, Seoul 06351, Korea; beomki.lee@skku.edu (B.L.); nayadoo@hanmail.net (H.-D.P.)
4 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea;
yoonsunjoo@gmail.com
5 Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of
Medicine, Seoul 06351, Korea; dr99.park@samsung.com
6 Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine,
Seoul 06351, Korea
7 Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan
University School of Medicine, Seoul 06351, Korea; leukemia1@skku.edu (C.W.J.); silk.ahn@samsung.com (M.-J.A.)
* Correspondence: taegunshin@skku.edu (T.G.S.); eskang@skku.edu (E.-S.K.); Tel.: +82-2-3410-2053 (T.G.S.);
+82-2-3410-2703 (E.-S.K.)
† These authors contributed equally to this work.
Usefulness of Presepsin for the Early Detection of Infectious Complications after Elective Colorectal Surgery, Compared with C-Reactive Protein and Procalcitonin
Erika Amanai Hirosaki University Hospital, Kishiko Nakai (kishiko_sk1064@yahoo.co.jp) https://orcid.org/0000-0002-6618-7803, Junichi Saito Hirosaki University Hospital, Eiji Hashiba Hirosaki University Hospital, Takuya Miura Hirosaki University Graduate School of Medicine, Hajime Morohashi Hirosaki University Graduate School of Medicine, Yoshiyuki Sakamoto Hirosaki University Graduate School of Medicine, Akio Mikami Hirosaki University Hospital, Kenichi Hakamada Hirosaki University Graduate School of Medicine, Kazuyoshi Hirota Hirosaki University Graduate School of Medicine.The Role and Validity of Diagnostic Biomarkers in Late-Onset Neonatal Sepsis
Patience Mwesigye1, Fizza Rizwan2, Niazy Alassaf3, Rizwan Khan31 InternalMedicine,UniversityofLimerick,Limerick,IRL
2 InternalMedicine,MedicalUniversityofSofia,Sofia,BGR
3 Neonatology, University Maternity Hospital, Limerick, Limerick, IRL
Corresponding author: Patience Mwesigye, patiencehonors@gmail.com
Presepsin as Early Marker of Sepsis in Emergency Department: A Narrative Review
Andrea Piccioni1, Michele Cosimo Santoro1,*, Tommaso de Cunzo2, Gianluca Tullo2, Sara Cicchinelli1, Angela Saviano2, Federico Valletta2, Marco Maria Pascale1, Marcello Candelli1, Marcello Covino1,2 and Francesco Franceschi1,21 Emergency Medicine Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy; andrea.piccioni@policlinicogemelli.it (A.P.); sara.cicchinelli@policlinicogemelli.it (S.C.);
marcomaria.pascale@policlinicogemelli.it (M.M.P.); marcello.candelli@policlinicogemelli.it (M.C.);
marcello.covino@policlinicogemelli.it (M.C.); francesco.franceschi@policlinicogemelli.it (F.F.)
2 Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy; tomdecunzo@gmail.com (T.d.C.); gianlucatullo@gmail.com (G.T.); saviange@libero.it (A.S.); fede.valletta@gemelli.com (F.V.)
*Correspondence: michelecosimo.santoro@policlinicogemelli.it
Evaluation of the Diagnostic and Prognostic Value of CSF Presepsin Levels in Patients with Postneurosurgical Ventriculitis/Meningitis
Guanghui Zheng1–3,*, Chenxi Zhang1–3,*, Guojun Zhang1–3, Chunqing Shao1–31Department of Clinical Diagnosis, Laboratory of Beijing Tiantan Hospital and Capital Medical University, Beijing, People’s Republic of China; 2NMPA Key Laboratory for Quality Control of in vitro Diagnostics, National Medical Products Administration, Beijing, People’s Republic of China; 3Beijing Engineering Research Center of Immunological Reagents Clinical Research, Beijing Municipal Science and Technology Commission, Beijing, People’s Republic of China
*These authors contributed equally to this work
Usefulness of presepsin in predicting the prognosis of patients with sepsis or septic shock: a retrospective cohort study
Jeong Suk Koh, Yoon Joo Kim, Da Hyun Kang, Jeong Eun Lee, Song-I LeeDepartment of Pulmonary and Critical Care Medicine, Chungnam National University School of Medicine, Daejeon, Korea
Presepsin and prognostic nutritional index are predictors of septic acute kidney injury, renal replacement therapy initiation in sepsis patients, and prognosis in septic acute kidney injury patients: a pilot study
Yuichiro Shimoyama1•, Osamu Umegaki1, Noriko Kadono1 and Toshiaki Minami2* Correspondence: shimocchiliebesfreud512@yahoo.co.jp
1 Department of Anesthesiology, Osaka Medical College, Intensive Care Unit, Osaka Medical College Hospital, 2-7 Daigaku-machi, Takatsuki, Osaka 569-8686, Japan
Presepsin level in predicting patients in-hospital mortality from sepsis under sepsis-3 criteria
Miao-Yun Wen1,*, Lin-Qiang Huang1,*, Fan Yang1,2, Jing-Kun Ye1,3, Geng-Xin Cai1,2, Xu-Sheng Li1,3, Hong-Guang Ding1, Hong-Ke Zeng11 Department of Emergency and Critical Care Medicine, Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences, Guangzhou, People’s Republic of China; 2 School of Medicine, South China University of Technology, Guangzhou, People’s Republic of China; 3The Second School of Clinical Medicine, Southern Medical University, Guangzhou, People’s Republic of China
Presepsin as a Diagnostic and Prognostic Biomarker in Sepsis
Dimitrios Velissaris1, Nicholas Zareifopoulos2, 3, Vasileios Karamouzos4, Evangelos Karanikolas5, Charalampos Pierrakos6, Ioanna Koniari7, Menelaos Karanikolas82 Department of Psychiatry, General Hospital of Nikaia, Piraeus "Agios Panteleimon", Athens, GRC 3Department of Internal Medicine, University of Patras School of Health Sciences, Patras, GRC
4 Intensive Care Unit, General University Hospital of Patras, Patras, GRC
5 Department of Internal Medicine, University of Patras, Patras, GRC
6 Intensive Care Unit, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, BEL
7 Department of Electrophysiology and Device, University Hospital of South Manchester NHS Foundation Trust, Manchester, GBR
8 Department of Anesthesiology, Washington University School of Medicine, St. Louis, USA
Corresponding author: Nicholas Zareifopoulos, nizareifopoulos@gmail.com
Novel Diagnostics and Therapeutics in Sepsis
Kieran Leong 1, Bhavita Gaglani 2 , Ashish K. Khanna 2,3, Michael T. McCurdy 1,*1 Division of Pulmonary & Critical Care, University of Maryland School of Medicine, Baltimore, MD 21201, USA; kleong@som.umaryland.edu
2 Department of Anesthesiology, Section on Critical Care Medicine, Wake Forest University Hospital, Winston-Salem, NC 27157, USA; bgaglani@wakehealth.edu (B.G.); ashish@or.org (A.K.K.)
3 Department of Outcomes Research, Outcomes Research Consortium, Cleveland, OH 44195, USA
* Correspondence: drmccurdy@gmail.com
Presepsin values and Prognostic Nutritional Index predict mortality in intensive care unit patients with sepsis: a prospective observational study
Yuichiro Shimoyama ( icu003@osaka-med.ac.jp )Osaka Medical College
Osamu Umegaki
Osaka Medical College: Osaka Ika Daigaku
Noriko Kadono
Osaka Medical College: Osaka Ika Daigaku
Toshiaki Minami
Osaka Medical College: Osaka Ika Daigaku
Presepsin as a Potential Prognostic Marker for Sepsis According to Actual Practice Guidelines
Alice Nicoleta Dragoescu 1, Vlad Padureanu 2,* , Andreea Doriana Stanculescu 1,*, Luminit,a Cristina Chiut,u 1,Dan Nicolae Florescu 3, Ioana Andreea Gheonea 4, Rodica Padureanu 5 , Alex Stepan 6, Costin Teodor Streba 7,
Andrei Ioan Drocas,
8, Adriana Mihaela Ciocâlteu-Ionescu 3, Valeriu MarinS,
urlin 9 and Octavian
Craiova, Romania; alice.dragoescu@yahoo.com (A.N.D.); luminita.chiutu@gmail.com (L.C.C.)
2 Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
3 Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
nicku_dan@yahoo.co.uk (D.N.F.); adriana_ciocalteu@yahoo.com (A.M.C.-I.)
4 Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, 200349
Craiova, Romania; iagheonea@gmail.com
5 Department of Biochemistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
zegheanurodica@yahoo.com
6 Department of Pathology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
astepan76@yahoo.com
7 Department of Research Methodology, University of Medicine and Pharmacy of Craiova, 200349 Craiova,
Romania; costinstreba@gmail.com
8 Department of Urology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania;
andrei_drocas@yahoo.com (A.I.D.); pdragoescu@yahoo.com (O.P.D.)
9 Department of Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
vsurlin@gmail.com
* Correspondence: vldpadureanu@yahoo.com (V.P.); stanculescu.andreea@yahoo.com (A.D.S.)
Clinical Value of Presepsin in Comparison to hsCRP as a Monitoring and Early Prognostic Marker for Sepsis in Critically Ill Patients
Elham A. Hassan 1,*, Abeer S. Abdel Rehim 1, Asmaa O. Ahmed 2, Hanan Abdullahtif 2 andAlaa Attia 3
1 Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University,
Assiut 71111, Egypt; sharafabeer@yahoo.com
2 Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut 71111, Egypt;
asomar_12@yahoo.com (A.O.A.); Abdlatif@aun.edu.eg (H.A.)
3 Department of Anesthesia and Intensive Care, Faculty of Medicine, Assiut University, Assiut 71111, Egypt;
alaa.atya@med.au.edu.eg
* Correspondence: mam_elham75@yahoo.com; Tel.: +201002963415; Fax: +20882333327
The Utility of Neutrophil CD64 and Presepsin as Diagnostic, Prognostic, and Monitoring Biomarkers in Neonatal Sepsis
Heba E. Hashem ,1 Rania M. Abdel Halim,1 Sherin A. El Masry ,1 Amira M. Mokhtar ,1and Noureldin M. Abdelaal 2
1Clinical Pathology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
2Pediatric and Neonatology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Correspondence should be addressed to Heba E. Hashem; hebaezzat@med.asu.edu.eg
Received 9 July 2020; Revised 16 August 2020; Accepted 22 September 2020; Published 2 November 2020
Диагностическое и прогностическое значение уровня пресепсина при инфекционно-воспалительных заболеваниях у недоношенных новорожденных
Л.Н. Журавлева, В.И. НовиковаВитебский государственный медицинский университет
Diagnostic and prognostic value of the presepsin level in inflammatory infectious
diseases in preterm newborns
L.N. Zhuravleva, V.I. Novikova
Vitebsk State Medical University, Vitebsk, Belarus
Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C‑reactive protein: a systematic review and meta‑analysis
Chin‑Chieh Wu1, Hao‑Min Lan2, Shih‑Tsung Han3, Chung‑Hsien Chaou3, Chun‑Fu Yeh4, Su‑Hsun Liu2,5,6 Clinical Informatics and Medical Statistics Research Center, Chang Gung
University, 5 Fu‑Shin Street, Gueishan Village, Taoyuan 333, Taiwan
Full list of author information is available at the end of the article
Presepsin as a Potential Prognostic Marker for Sepsis According to Actual Practice Guidelines
Alice Nicoleta Dragoescu 1, Vlad Padureanu 2,* , Andreea Doriana Stanculescu 1,*, Luminit,a Cristina Chiut,u 1,Dan Nicolae Florescu 3, Ioana Andreea Gheonea 4, Rodica Padureanu 5 , Alex Stepan 6, Costin Teodor Streba 7,
Andrei Ioan Drocas,
8, Adriana Mihaela Ciocâlteu-Ionescu 3, Valeriu MarinS,
urlin 9 and Octavian
Craiova, Romania; alice.dragoescu@yahoo.com (A.N.D.); luminita.chiutu@gmail.com (L.C.C.)
2 Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
3 Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
nicku_dan@yahoo.co.uk (D.N.F.); adriana_ciocalteu@yahoo.com (A.M.C.-I.)
4 Department of Radiology and Medical Imaging, University of Medicine and Pharmacy of Craiova, 200349
Craiova, Romania; iagheonea@gmail.com
5 Department of Biochemistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
zegheanurodica@yahoo.com
6 Department of Pathology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
astepan76@yahoo.com
7 Department of Research Methodology, University of Medicine and Pharmacy of Craiova, 200349 Craiova,
Romania; costinstreba@gmail.com
8 Department of Urology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania;
andrei_drocas@yahoo.com (A.I.D.); pdragoescu@yahoo.com (O.P.D.)
9 Department of Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania;
vsurlin@gmail.com
* Correspondence: vldpadureanu@yahoo.com (V.P.); stanculescu.andreea@yahoo.com (A.D.S.)
Diagnostic value of procalcitonin and presepsin for sepsis in critically ill adult patients: a systematic review and meta-analysis
this work.
6Division of Trauma and Surgical Critical Care, Osaka General Medical Center,
3-1-56 Bandai-Higashi, Sumiyoshi-ku, Osaka 558-8558, Japan
Full list of author information is available at the end of the article
Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C‑reactive protein: a systematic review and meta‑analysis
Chin‑Chieh Wu1, Hao‑Min Lan2, Shih‑Tsung Han3, Chung‑Hsien Chaou3, Chun‑Fu Yeh4, Su‑Hsun Liu2,5,6 Clinical Informatics and Medical Statistics Research Center, Chang Gung
University, 5 Fu‑Shin Street, Gueishan Village, Taoyuan 333, Taiwan
Full list of author information is available at the end of the article
The accuracy assessment of presepsin (sCD14-ST) for mortality prediction in adult patients with sepsis and a head-to-head comparison to PCT: a meta-analysis
Ying Zhu1,2Xuehui Li1
Peiyan Guo1
Yuhan Chen3
Jiandong Li1
The Seventh Medical Center of PLA
General Hospital, Beijing, People’s
Republic of China; 2Department of
Respiratory and Critical Care Medicine,
Shanghai East Hospital, Tongji University,
Shanghai, People’s Republic of China;
3Affiliated BaYi Children’s Hospital, The
Seventh Medical Center of PLA General
Hospital, Beijing, People’s Republic of
China; 4Department of Anesthesiology,
Air Force Medical Center, PLA, Beijing,
People’s Republic of China
Comparative study between complete blood picture indices and presepsin as early prognostic markers in septic shock patients
Faculty of Medicine, Alexandria University, Alexandria, Egypt
Individual and combined bioscore model of presepsin, procalcitonin, and high sensitive C - reactive protein as biomarkers for early diagnosis of paediatric sepsis
Samuel Asamoah Sakyi a,*, Anthony Enimil b, David Kwabena Adu a,c, Richard Dadzie Ephraim d,Kwabena Owusu Danquah e, Linda Fondjo a, David Baidoe-Ansah f, Prince Adoba a,
b Child Health Directorate, Komfo Anokye Teaching Hospital, School of Medical Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi,
Ghana
c College of Health and Well-Being, Kintampo, Ghana
d Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana
e Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
f Department of Physiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
g Laboratory Diagnostics, Ghana Health Service, Dansoman Polyclinic, Accra, Ghana
Association between elevation of plasma biomarkers and monocyte dysfunction and their combination in predicting sepsis: An observational single-centre cohort study
Jiabao Li1, Ziren Tang1, Miaorong Xie2, Chenchen Hang1,Medical University, PR China
2Department of Emergency Medicine, Beijing Friendship Hospital, Capital
Medical University, PR China
Presepsin values and Prognostic Nutritional Index predict mortality in intensive care unit patients with sepsis: a prospective observational study
Yuichiro Shimoyama ( icu003@osaka-med.ac.jp )Osaka Medical College
Osamu Umegaki
Osaka Medical College: Osaka Ika Daigaku
Noriko Kadono
Osaka Medical College: Osaka Ika Daigaku
Toshiaki Minami
Osaka Medical College: Osaka Ika Daigaku
Can presepsin uniformly respond to various pathogens? - an in vitro assay of new sepsis marker
Yusuke Koizumi1,2* , Daisuke Sakanashi2, Tetsuo Mohri2, Hiroki Watanabe1,2, Arufumi Shiota2, Nobuhiro Asai1,2,1Department of Clinical Infectious Diseases, Aichi Medical University Hospital,
1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan
2Department of Infection Control, Aichi Medical University Hospital,
Nagakute, Aichi, Japan
Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis
College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea
Full list of author information is available at the end of the article
Presepsin values as markers of severity of sepsis
ª ICU Department, University Clinic of Infectious Diseases, Alexander Flemingu, 10000 Pristina, Kosovo
ᵇ ICU Department, University Hospital for Infectious Diseases “Dr. Fran Mihaljevic”, Mirogojska 8,
10000 Zagreb, Croatia
Role of Plasma Presepsin, Procalcitonin and C-reactive Protein Levels in Determining the Severity and Mortality of Community-Acquired Pneumonia in the Emergency Department
Izzettin Hur1, Seda Ozkan2;*, Ali Halici3, Kerim Abatay4,Ministry of Health Pursaklar State
Hospital, Ankara, Turkey
2Department of Emergency Medicine,
Cerrahpasa Faculty of Medicine, Istanbul
University-Cerrahpasa, Istanbul, Turkey
3Department of Emergency Medicine,
Ministry of Health Polatlı State Hospital,
Ankara, Turkey
4Department of Emergency Medicine,
Ministry of Health Muş State Hospital,
Muş, Turkey
5Department of Emergency Medicine,
Ministry of Health Dr. Nafiz Korez Sincan
State Hospital, Ankara, Turkey
6Department of Clinical Biochemistry,
Diskapi Yildirim Beyazit Training &
Research Hospital, Ankara, Turkey
Impact of initial plasma presepsin level for clinical outcome in hospitalized patients with pneumonia
Japan
Contributions: (I) Conception and design: M Ugajin; (II) Administrative support: All authors; (III) Provision of study materials or patients: All authors;
(IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: M Ugajin; (VI) Manuscript writing: All authors; (VII) Final
approval of manuscript: All authors.
Correspondence to: Motoi Ugajin, MD. Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, 2-52 Kouzouji-cho Kita, Kasugai
City 487-0016, Japan. Email: ugarin2001@yahoo.co.jp.
Presepsin as a biomarker in perioperative medicine
Jessica HANDKE 1, Ornella PIAZZA 2 *, Jan LARMANN 1,and Surgery, University of Salerno, Baronissi, Salerno, Italy; 3Department of Surgical and Biomedical Sciences,
University of Perugia, Perugia, Italy
The novel early predictive marker presepsin for postoperative pancreatic fistula: A pilot study
Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis
College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea
Full list of author information is available at the end of the article
Role of Plasma Presepsin, Procalcitonin and C-reactive Protein Levels in Determining the Severity and Mortality of Community-Acquired Pneumonia in the Emergency Department
Izzettin Hur1, Seda Ozkan2;*, Ali Halici3, Kerim Abatay4,Ministry of Health Pursaklar State
Hospital, Ankara, Turkey
2Department of Emergency Medicine,
Cerrahpasa Faculty of Medicine, Istanbul
University-Cerrahpasa, Istanbul, Turkey
3Department of Emergency Medicine,
Ministry of Health Polatlı State Hospital,
Ankara, Turkey
4Department of Emergency Medicine,
Ministry of Health Muş State Hospital,
Muş, Turkey
5Department of Emergency Medicine,
Ministry of Health Dr. Nafiz Korez Sincan
State Hospital, Ankara, Turkey
6Department of Clinical Biochemistry,
Diskapi Yildirim Beyazit Training &
Research Hospital, Ankara, Turkey
*Correspondence
sedacil@gmail.com
(Seda Ozkan)
Presepsin as a biomarker in perioperative medicine
Jessica HANDKE 1, Ornella PIAZZA 2 *, Jan LARMANN 1,Simonetta TESORO 3, Edoardo DE ROBERTIS 3
University of Perugia, Perugia, Italy
Presepsin as a Biomarker for Sepsis Evolutions in Diabetis
Comparative study between complete blood picture indices and presepsin as early prognostic markers in septic shock patients
Comparative study between complete blood picture indices and presepsin as early prognostic
markers in septic shock patients, Egyptian Journal of Anaesthesia, 36:1, 118-125, DOI:
10.1080/11101849.2020.1789403
Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis
1Department of Pediatrics, Severance Children’s Hospital, Yonsei University
College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea
Full list of author information is available at the end of the article
Presepsin Level Correlates with the Development of Moderate Coronary Artery Calcifications in Hemodialysis Patients: A Preliminary Cross-Section Design Study
Ahmed F ElhabashiLeena Sulaibeekh
Nahed Seddiq
Salman Alali
Amjad K Abdulmajeed
Medical Services, Riffa, Kingdom of
Bahrain
Presepsin values as markers of severity of sepsis
ᵇ ICU Department, University Hospital for Infectious Diseases “Dr. Fran Mihaljevic”, Mirogojska 8,
10000 Zagreb, Croatia
ͨ “PROLAB” Biochemical Laboratory, Mark Dizdari, 10000 Pristina, Kosovo
٭Correspondence: ajete.aliu@gmail.com (Ajete Aliu-Bejta), barsicbruno@gmail.com (Bruno Baršić)
Diagnostic Value of Presepsin for Bacterial Infection in Cirrhosis: A Pilot Study
Simone Novellia, *, Vincenzo Morabitob , Franco Rubertob , Fabiano Binib , Franco Marinozzib , Francesco Puglieseb , Pasquale Berlocob , and Renzo Pretagostinib a Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Rome, Italy; and b Department of General Surgery and Organ Transplantation, Sapienza University of Rome, Rome, ItalyPresepsin as a predictive biomarker of severity in COVID-19: a case series
Ai Fukada1, Yutaro Kitagawa1, Masaru Matsuoka1, Jun Sakai2, Kazuo Imai2Tarumoto Norihito2, Yuta Orihara1, Rieko Kawamura1, Shinichi Takeuchi1
Shigefumi Maesaki2, Takuya Maeda1, 3
3Department of Laboratory Medicine, Saitama Medical University, Saitama, Japan
Presepsin as a novel diagnostic biomarker for differentiating active pulmonary tuberculosis from bacterial community acquired pneumonia
Zhi-jiang Qia,1, Han Yua,1, Jing Zhangb, Chun-sheng Lia,⁎a Emergency Department of Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
b Emergency Department of Beijing Tuberculosis Research Institute, Capital Medical University, Beijing 101149, China
Impact of initial plasma presepsin level for clinical outcome in hospitalized patients with pneumonia
Motoi Ugajin1, Yu Matsuura2, Kei Matsuura2, Hiroshi Matsuura21Department of Respiratory Medicine, 2Department of Internal Medicine, Nagoya Tokushukai General Hospital, Kasugai City, Aichi Prefecture,
Japan
Contributions: (I) Conception and design: M Ugajin; (II) Administrative support: All authors; (III) Provision of study materials or patients: All authors;
(IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: M Ugajin; (VI) Manuscript writing: All authors; (VII) Final
approval of manuscript: All authors.
Correspondence to: Motoi Ugajin, MD. Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, 2-52 Kouzouji-cho Kita, Kasugai
City 487-0016, Japan. Email: ugarin2001@yahoo.co.jp.
Role of Presepsin (sCD14-ST) and the CURB65 scoring system in predicting severity and outcome of community-acquired pneumonia in an emergency department
Emergency Department, Beijing Chao-Yang Hospital of the Capital Medical University,Beijing 100020, China
Received 29 January 2014; accepted 6 May 2014
Available online 2 June 2014
Impact of initial plasma presepsin level for clinical outcome in hospitalized patients with pneumonia
Motoi Ugajin1, Yu Matsuura2, Kei Matsuura2, Hiroshi Matsuura21Department of Respiratory Medicine, 2Department of Internal Medicine, Nagoya Tokushukai General Hospital, Kasugai City, Aichi Prefecture,
Japan
Contributions: (I) Conception and design: M Ugajin; (II) Administrative support: All authors; (III) Provision of study materials or patients: All authors;
(IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: M Ugajin; (VI) Manuscript writing: All authors; (VII) Final
approval of manuscript: All authors.
Correspondence to: Motoi Ugajin, MD. Department of Respiratory Medicine, Nagoya Tokushukai General Hospital, 2-52 Kouzouji-cho Kita, Kasugai
City 487-0016, Japan. Email: ugarin2001@yahoo.co.jp.
The role of presepsin in the diagnosis of chronic obstructive pulmonary disease acute exacerbation with pneumonia
Ali Halıcı1, I˙zzettin Hu¨ r1, Kerim Abatay1, Esra C¸ etin2, Filiz Halıcı3 & Seda O¨ zkan*,41Department of Emergency Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital,
06145, Ankara, Turkey
2Department of Biochemistry, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital, 06145, Ankara,
Turkey
3Department of Family Medicine, University of Health Sciences, Diskapi Yildirim Beyazit Training & Research Hospital,
06145, Ankara, Turkey
4Department of Emergency Medicine, University of Istanbul-Cerrahpasa, Faculty of Medical, 34098, Istanbul, Turkey
*Author for correspondence: Tel.: +90 212 414 3434; sedacil@gmail.com
Пресепсин и стратификация рисков у пациентов с SARS-CoV-2 (COVID-19)
Presepsin in risk stratification of SARS-CoV-2 patientsClinica Chimica Acta Available online 22 April 2020
Martina Zaninotto aMonica Maria Mion aChiara Cosmaa Daniela Rinaldi aMarioPlebaniab
https://doi.org/10.1016/j.cca.2020.04.020Get rights and content
Presepsin and procalcitonin as predictors of sepsis based on the new Sepsis-3 definitions in obstructive acute pyelonephritis
Department of Urology, Kyorin University School of Medicine, Shikawa
6-20-2, Mitaka, Tokyo 181-8611, Japan
Presepsin as a New Marker for Early Detection Neonatal Sepsis in Al-Quwayiyah General Hospital Riyadh, KSA
2Microbiology Laboratory, Al-Quwayiyah General Hospital, Riyadh, KSA.
3Department of Pediatrics, Faculty of Medicine, Benha University, Egypt.
4Nursery Department, Al-Quwayiyah General Hospital, Riyadh, KSA.а
Usefulness of presepsin as diagnostic and prognostic marker of sepsis in daily clinical practice
Matjaz Jereb1, Matej Mavric1, Miha Skvarc2, Alja Drobnic1, Spela Dolenc1, Natalija Planinc Strunjas1, Boris Luksic3, Nina Grasselli Kmet11 Department of Infectious Diseases, University Medical Centre, Ljubljana, Slovenia
2 Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
3 Department of Infectious Diseases, Clinical Hospital Center, Split, Croatia
Are presepsin and resistin better markers for bacterial infection in patients with decompensated liver cirrhosis?
Petra Fischera, Crina Grigorasa, Anca Bugariua, Oana Nicoara-Farcaua, Horia Stefanescub,Andreea Beneab, Adina Hadadec, Simona Margaritc, Zeno Sparcheza,b, Marcel Tantaua,b,
Daniela Ionescuc,d,1, Bogdan Procopeta,b,∗,1
a University of Medicine and Pharmacy “Iuliu Hatieganu”, 3rd Medical Clinic, Hepatology Department, Cluj-Napoca, Romania
b Regional Institute of Gastroenterology and Hepatology “Prof. Dr. Octavian Fodor”, Hepatology Department, Cluj-Napoca, Romania
c University of Medicine and Pharmacy “Iuliu Hatieganu”, Department of Anesthesia and Intensive Care I, Cluj-Napoca, Romania
d Outcome Research Consortium, Cleveland, USA
The value of serum presepsin in differentiating Gram-negative bacteria from Gram-positive bacteria and fungal infection in sepsis patients
2Department of Emergency and Critical Care Medicine, Guangdong Provincial People’s Hospital and
Guangdong Academy of Medical Sciences, Guangzhou 510080, China
Corresponding author:Wen Miaoyun, Email: wenmiaoyun041105@163.com
The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic review
Lin Ruan1*, Guan-Yu Chen1, Zhen Liu1,2†, Yun Zhao1,2†, Guang-Yu Xu1,2†, Shu-Fang Li1,2†, Chun-Ni Li1,2†,Lin-Shan Chen1,3† and Zheng Tao1,3†
Роль биохимических маркеров воспаления у пациентов с нейтропенией после химиотерапии
Ю.Н. Дубинина1, В.О. Саржевский2, В.Я. Мельниченко2
1 Клиника амбулаторной онкологии и гематологии, ул. Молодогвардейская, д. 2, корп. 1, Москва, Российская Федерация, 121467
2 ФГБУ «Национальный медико-хирургический центр им. Н.И. Пиро-
гова», Минздрава России, ул. Нижняя Первомайская, д. 70, Москва,
Российская Федерация, 105203
Sepsis diagnosis and monitoring – procalcitonin as standard, but what next?
Magdalena Mierzchała-Pasierb, Department of MedicalBiochemistry, Wroclaw Medical University,
10 Chalubinskiego St., 50-368 Wroclaw, Poland,
e-mail: magdalena.mierzchala-pasierb@umed.wroc.pl
Clinical evaluation of presepsin considering renal function
Masashi MiyoshiID1*, Yusuke Inoue1, Mai Nishioka1, Akishige Ikegame1, Takayuki Nakao1,
Seiji Kishi2, Toshio Doi2, Kojiro Nagai2*
1 Department of Medical Technology, Tokushima University Hospital, Tokushima, Japan, 2 Department of
Nephrology, Tokushima University Hospital, Tokushima, Japan
Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis
Seo Hee Yoon1, Eun Hwa Kim2, Ha Yan Kim2 and Jong Gyun Ahn1
1Department of Pediatrics, Severance Children’s Hospital, Yonsei University
College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea
Full list of author information is available at the end of the article
Presepsin as a predictor of sepsis outcome in comparison with procalcitonin and C-reactive protein
University, Beni Suef, bCritical Care Medicine
Department, Cairo University, Giza, Egypt
Correspondence to Khaled M. Taema, MD,
7985 Almadeena Almonawara Street,
Mokattam, Cairo 11571, Egypt.
Tel: +20 100 041 2603;
e-mail: khaled.toaima@kasralainy.edu.eg
Presepsin and fetuin-A dyad for the diagnosis of proven sepsis in preterm neonates
Halil Değirmencioğlu1, Buse Ozer Bekmez2* , Turan Derme2, Mehmet Yekta Öncel3, Fuat Emre Canpolat2 andДиагностические характеристики пресепсина при позднем неонатальном сепсисе у недоношенных новорожденных.
Пограничный уровень - 823 пг/мл
Чувствительность – 88,9%; специфичность – 88,9%, AUC ROC – 0,939;
Положительное предиктивное значение – 72,7%
Отрицательное предиктивное значение - 87,5 %
Presepsin level in predicting patients’ in-hospital mortality from sepsis under sepsis-3 criteria
Miao-Yun Wen1,*Lin-Qiang Huang1,*
Fan Yang1,2
Jing-Kun Ye1,3
Geng-Xin Cai1,2
Xu-Sheng Li1,3
Hong-Guang Ding1
Care Medicine, Guangdong Provincial
People’s Hospital and Guangdong
Academy of Medical Sciences,
Guangzhou, People’s Republic of China;
2School of Medicine, South China
University of Technology, Guangzhou,
People’s Republic of China; 3The Second
School of Clinical Medicine, Southern
Medical University, Guangzhou, People’s
this work
The accuracy assessment of presepsin (sCD14-ST) for mortality prediction in adult patients with sepsis and a head-to-head comparison to PCT: a meta-analysis
Ying Zhu1,2Xuehui Li1
Peiyan Guo1
Yuhan Chen3
Jiandong Li1
The Seventh Medical Center of PLA
General Hospital, Beijing, People’s
Shanghai, People’s Republic of China;
3Affiliated BaYi Children’s Hospital, The
Seventh Medical Center of PLA General
Hospital, Beijing, People’s Republic ofChina;
People’s Republic of China
Diagnostic Value and Prognostic Use of Presepsin Versus Procalcitonin in Sepsis
Deepak P. Venugopalan , Gopalakrishna Pillai , Sajitha Krishnan1. Internal Medicine, Aster Medcity, Kochi, IND 2. Internal Medicine, Amrita Institute of Medical
Sciences and Research Centre, Kochi, IND
Corresponding author: Deepak P. Venugopalan, drdeepakvenugopalan@gmail.com
Disclosures can be found in Additional Information at the end of the article
Сравнительная оценка активности эндотоксина и (точности) различных биомаркеров (ПСП, ПКТ, лактат, ИЛ-6) по отношению к инфекциям и исходам у пациентов, поступивших в отделение неотложной терапии
Toshiaki Ikeda 1,*, Hidenobu Kamohara 1, Shingo Suda 1, Takeo Nagura 1, Mikiko Tomino 2,Masatoshi Sugi 2 and Zen’ichiro Wajima 2
1 Division of Critical Care and Emergency Medicine, Tokyo Medical University Hachioji Medical Center,
Tokyo 193-0998, Japan
2 Department of Anesthesiology, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan
* Correspondence: toshi@tokyo-med.ac.jp; Tel.: +81-426-65-5611
Utility of Presepsin for Diagnosis of Infected Acute Necrotizing Pancreatitis
Oleksandr Rotar1, Igor Khomiak2, Michail Nazarchuck3, Vasyl Rotar1, Andrii Khomiak2, KrishnaTaneja1, Sitlana Railianu1
1Bukovinian State Medical University, Chernivtsi, Ukraine
2O.O. Shalimov National Institute of Surgery and Transplantology, Kyiv, Ukraine
35th City Clinical Hospital, Minsk, Belarus
Soluble CD14 subtype (sCD14-ST) as biomarker in neonatal early-onset sepsis and late-onset sepsis: a systematic review and meta-analysis
Iris van Maldeghem , Charlotte M. Nusman and Douwe H. Visser
1Department of Pediatrics, Emma Children’s Hospital, Amsterdam UMC,
University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
Full list of author information is available at the end of the article.
«Пресепсин (sCD14-ST) как биомаркер раннего и позднего неонатального сепсиса: систематический обзор и мета-анализ» ПСП – многообещающий маркер раннего и позднего неонатального сепсиса (РНС и ПНС). Разница между средними уровнями ПСП при РНС и ПНС подчеркивает важность того, что РНС и ПНС это две различные патологические сущности (different disease entities), при которых образцы измеренные при РНС характеризуют преклиническую стадию инфекции, а при ПНС - ее клиническую стадию. В будущей ежедневной практике ПСП может быть ценным маркером для исключения РНС до начала антибиотикотерапии.
Пресепсин в диагностике нозокомиальной инфекции центральной нервной системы
С.А. Абудеев1, К.В. Киселев2, О.В. Паринов1, Ю.Д. Удалов1, М.В. Забелин1, А.С. Самойлов1,К.А. Попугаев1*
Отделение нейрореанимации и нейроанестезиологии
1 ФГБУ «ГНЦ — ФМБЦ имени А.И. Бурназяна» ФМБА,
Российская Федерация, 123098 Москва, ул. Маршала Новикова, д. 23
2 ГБОУ ВО «РНИМУ имени Н.И. Пирогова» Минздрава России,
Российская Федерация, 117997 Москва, ул. Островитянова, д. 1
* Контактная информация: Попугаев Константин Александрович, доктор медицинских наук, заведующий отделением нейрореанимации
ФГБУ ГНЦ ФМБЦ А.И. Бурназяна ФМБА России. E-mail: stan.popugaev@yahoo.com
Пресепсин - маркер тяжести септическоо процесса у больных с некротическим панкреатитом
A Patient of Using Presepsin to Diagnose Streptococcal Toxic Shock Syndrome during Anticancer Drug Treatment
Gaku TakahashiDepartment of Critical Care, Disaster and GeneralMedicine, School of Medicine, Iwate Medical University, Japan
Correspondence should be addressed to Gaku Takahashi; gakut@iwate-med.ac.jp
Received 10 December 2018; Revised 18 March 2019; Accepted 2 April 2019; Published 16 April 2019
Academic Editor: Ricardo Jorge Dinis-Oliveira
Значение пресепсина для прогнозирования краткосрочной динамики состояния и предотвращения избыточности антибактериальной терапии у пациентов с нозокомиальными инфекциями
К.А. Загородникова, Л.Б. Гайковая, А.Т. Бурбелло, М.А. Костицына,М.В. Покладова, А.И. Ермаков, М.В. Комок
Северо-Западный государственный медицинский университет им. И.И.Мечникова, Санкт-Петербург, Россия
The emerging role of Presepsin for diagnosis and monitoring of neonatal sepsis
Mitsubishi Chemical Europe GmbHWillstätter Str. 30, 40549 Düsseldorf, Germany
Phone: +49 (0) 211 - 5 20 54 10
Facsimile: +49 (0) 211 - 59 12 72
email: Pathfast@mc-e.de
Первый опыт применения селективной лпс-адсорбции в комплексной интенсивной терапии детей с грамотрицательным сепсисом после кардиохирургических операций
Ярустовский М.Б., Абрамян М.В., Солдаткина А.О., Комардина Е.В.,Назарова Е.И., Плющ М.Г., Рогальская Е.А.
ФГБУ «НМИЦ сердечно-сосудистой хирургии им. А.Н. Бакулева»
Минздрава России, 121552, Москва, Россия
Clinical Value of Presepsin in Comparison to hsCRP as a Monitoring and Early Prognostic Marker for Sepsis in Critically Ill Patients
Elham A. Hassan 1,*, Abeer S. Abdel Rehim 1, Asmaa O. Ahmed 2, Hanan Abdullahtif 2 andAlaa Attia 3 1 Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University,
Assiut 71111, Egypt; sharafabeer@yahoo.com 2 Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut 71111, Egypt;
asomar_12@yahoo.com (A.O.A.); Abdlatif@aun.edu.eg (H.A.) 3 Department of Anesthesia and Intensive Care, Faculty of Medicine, Assiut University, Assiut 71111, Egypt;
alaa.atya@med.au.edu.eg
* Correspondence: mam_elham75@yahoo.com; Tel.: +201002963415; Fax: +20882333327
Can presepsin be used for screening invasive fungal infections?
Giuseppe Lippi 1 , Gianfranco Cervellin 21 Section of Clinical Biochemistry, University of Verona, Verona, Italy; 2 Emergency Department, University Hospital of Parma, Parma, Italy
Correspondence to: Prof. Giuseppe Lippi. Section of Clinical Biochemistry, University Hospital of Verona, Piazzale LA Scuro, 37134 Verona, Italy.
Email: giuseppe.lippi@univr.it
Low Levels of Procalcitonin or Presepsin Combined with Significantly Elevated C-reactive Protein May Suggest an Invasive Fungal Infection in Hematological Patients With Febrile Neutropenia
Igor Stoma1,2, Igor Karpov1, Anatoly Uss2, Svetlana Krivenko2, Igor Iskrov2, Natalia Milanovich2,Svetlana Vlasenkova2, Irina Lendina2, Kristina Belyavskaya2, Veranika Charniak2
Correspondence: Igor Stoma (e-mail: igor.stoma@gmail.com).
Пресепсин – новый биологический маркер в диагностике и контроле эффективности лечения сепсиса
В. Г. Кукес 1, 2 , В. Ф. Маринин 1 , Ю. В. Олефир 2 , Е. В. Ших 1 , А. Б. Прокофьев 1, 2 ,Д. О. Грапов 1 , Д. А. Вердиева 1 , Н. А. Румянцев 1, 2
1 Первый Московский государственный медицинский университет
им. И. М. Сеченова (Сеченовский Университет), Россия
2 Научный центр экспертизы средств медицинского применения, Москва, Россия
The Physiological Variation in Plasma Presepsin Levels During the Early Neonatal Period
Masahiro Ishii, 1 Takayuki Hoshina, 1 Shun Ichikawa, 1 Daisuke Shimizu, 1Shunsuke Araki, 1 Tadamune Kinjo, 1 Eiji Shibata, 2 Toru Hachisuga 2 and Koichi Kusuhara 1
1 Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Japan,
Kitakyushu, Fukuoka, Japan
2 Department of Obstetrics and Gynecology, School of Medicine, University of Occupational and Environmental
Health, Japan, Kitakyushu, Fukuoka, Japan
Роль современных маркеров системного воспаления в диагностике и прогнозировании течения инфекционного эндокардита
Л.А. БЕГАНСКАЯ1, А.П. РОЙТМАН1*, А.Г. МОРОЗОВ2, А.В. БУГРОВ1, Т.А. ФЕДОРОВА2, В.В. ДОЛГОВ11Кафедра клинической лабораторной диагностики Российской медицинской академии непрерывного последипломного
образования Российской Федерации, Москва, Россия; 2кафедра терапии ИПО Российской медицинской академии непрерывного
последипломного образования Российской Федерации, Москва, Россия
The usefulness of pleural fluid presepsin, C-reactive protein, and procalcitonin in distinguishing different causes of pleural effusions
Naoki Watanabe 1* , Tomoya Ishii 1 , Nobuyuki Kita 1 , Nobuhiro Kanaji 1 , Hiroyuki Nakamura 2 , Nobuki Nanki 3 ,Yutaka Ueda 4 , Yasunori Tojo 5 , Norimitsu Kadowaki 1 and Shuji Bandoh 1
The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic review
Lin Ruan 1* , Guan-Yu Chen 1 , Zhen Liu 1,2† , Yun Zhao 1,2† , Guang-Yu Xu 1,2† , Shu-Fang Li 1,2† , Chun-Ni Li 1,2† , Lin-Shan Chen 1,3† and Zheng Tao 1,3†† Zhen Liu, Yun Zhao, Guang-Yu Xu, Shu-Fang Li, Chun-Ni Li, Lin-Shan Chen and Zheng Tao contributed equally to this work.
1 Departments of Anesthesiology, Guangxi Medical University Affiliated Tumor Hospital, Naning, Guangxi, China
Full list of author information is available at the end of the article
Increased presepsin levels are associated with the severity of fungal bloodstream infections
Yuuki BambaID, Hiroshi MoroID*, Nobumasa Aoki, Takeshi Koizumi, Yasuyoshi Ohshima,Satoshi WatanabeID, Takuro Sakagami, Toshiyuki Koya, Toshinori Takada,
Toshiaki Kikuchi
Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical
and Dental Sciences, Niigata, Japan.
Значение пресепсина как раннего маркера гнойно-септических осложнений у пациентов с тяжелым панкреатитом
Н.Н. Салина*, В.П. Никулина, Р.Н. Борисов, М.А. ГодковЛаборатория клинической иммунологии, ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского Департамента здравоохранения
г. Москвы», Москва, Российская Федерация
Пресепсин спинномозговой жидкости – маркер нозокомиальных инфекций ЦНС
Sergey A. Abudeev1, Kirill V. Kiselev2, Nikolay M. Kruglyakov1, Ksenia A. Belousova1, InnaN. Lobanova1, Oleg V. Parinov1, Yuriy D. Udalov1, Maxim A. Zabelin1, Alexandr S.
Samoilov1, Evaldas Cesnulis3, Tim Killeen3 and Konstantin A. Popugaev1*
1 Burnazian State Research Center, Federal Medical-Biological Agency, Moscow, Russia, 2 Pirogov Russian National
Research Medical University, Russian Ministry of Education, Moscow, Russia, 3 Department of Neurosurgery, Klinik
Hirslanden, Zurich, Switzerland
Способ определения показаний к проведению селективной адсорбции эндотоксина у пациентов с сепсисом, вызванным грамотрицательными микроорганизмами
Автор(ы):Рогальская Екатерина Анатольевна (RU), Климович Людмила Григорьевна (RU), Плющ Марина Георгиевна (RU), Самсонова Наталья Николаевна (RU), Ярустовский Михаил Борисович (RU), Абрамян Марина Владимировна (RU).
Prognostic value of presepsin in adult patients with sepsis: Systematic review and metaanalysis
Hyun Suk Yang1, Mina Hur2*, Ahram Yi2, Hanah Kim2, Seungho Lee3, Soo-Nyung Kim41 Department of Cardiovascular Medicine, Research Institute of Medical Science, Konkuk University School
of Medicine, Seoul, Korea, 2 Department of Laboratory Medicine, Konkuk University School of Medicine,
Seoul, Korea, 3 School of Public Health, Seoul National University, Seoul, Korea, 4 Department of Obstetrics
and Gynecology, Konkuk University School of Medicine, Seoul, Korea
* dearmina@hanmail.net
Presepsin: Early Biomarker in Diagnosis of Sepsis in Emergency Department
Ovidiu Popa1, Diana Cimpoieșu1* and Carmen Dorobăț21Emergency Department, St. “Spiridon” Hospital Iași, “Gr. T. Popa” University of Medicine and Pharmacy, Iași, Romania
2Department of Infectious Disease, Clinic Infectious Diseases Hospital Iași, “Gr. T. Popa” University of Medicine and Pharmacy, Iași, Romania
Diagnostic Value of Presepsin in Sepsis
Silvana Teixeira Dal Ponte1*, Giordanna Andrioli 1, Luciano Passamani Diogo1, Renato Seligman2, Luciano Zubaran Goldani2, Andre Pinheiro Weber3, Gabriela Petitot Rezende4, Pauline Simas Machado41Emergency Physician, Emergency department, Hospital de Clinicas de Porto Alegre- Rs, Brazil
2Professor of Medicine, Universidade Federal do Rio Grande do Sul, Brazil
³Resident Emergency Medicine, Hospital de Pronto Socorro de Porto Alegre-RS, Brazil
4 Academic of Medicine, Universidade Federal do Rio Grande do Sul, Brazil
The role of presepsin, c-reactive protein and procalcitonin as a marker of therapy response and prognosis for late onset neonatal sepsis in preterm neonates
Dalima AW Astrawinata 1 , Risma Kerina Kaban 2 , Rosalina Dewi Roeslani 3 , Erna Parmawati 41 Department of Clinical Pathology, Faculty of Medicine University Indonesia/Dr. Cipto Mangunkusumo National General Hospital, Jakarta
2 Department of Pediatric, Faculty of Medicine University Indonesia/Dr. Cipto Mangunkusumo National General Hospital, Jakarta
3 Department of Pediatric, Faculty of Medicine University Indonesia/Dr. Cipto Mangunkusumo National General Hospital, Jakarta
4 Department of Clinical Pathology Medical Specialty Program, Faculty of Medicine University Indonesia/Dr.Cipto
Mangunkusumo National General Hospital, Jakarta.
Role of presepsin compared to C-reactive protein in sepsis diagnosis and prognostication
Mohamed El-Saied El-Shafie a , Khaled M. Taema a, ⇑ , Moataz M. El-Hallag a ,Abdallah Mohamed Abdallah Kandeel b
a, b
Critical Care Medicine, Cairo University, Egypt
Critical Care Medicine, El-Sahel Teaching Hospital, Egypt
Диагностическое и прогностическое значение биохимических маркеров инфекционных осложнений высокодозной химиотерапии с аутологичной трансплантацией гемопоэтических стволовых клеток при злокачественных лимфопролиферативных заболеваниях
В.О. Саржевский, Ю.Н. Дубинина, В.Я. Мельниченко VO Sarzhevskii, YuN Dubinina, VYa Mel’nichenkoФГБУ «Национальный медико-хирургический центр им. Н.И. Пиро-ова» Минздрава России, ул. Нижняя Первомайская, д. 70, Москва,
Российская Федерация, 105203
Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome: a systematic review and meta‐analysis
В статье приводится таблица разлиных маркеров сепсиса, их чувствительность и специфичность.Yong Liu 1† , Jun‐huan Hou 2,3† , Qing Li 2,3 , Kui‐jun Chen 2,3 , Shu‐Nan Wang 4 and Jian‐min Wang 2,3*
† Yong Liu and Jun-huan Hou contributed equally to this work
2 Research Institute of Surgery, Daping Hospital, Third Military Medical
University, Chongqing 400042, People’s Republic of China
Full list of author information is available at the end of the article
Влияние искусственных дыхательных путей на исходы интенсивной терапии пожилых пациентов с острыми нарушениями мозгового кровообращения
КОХНО В.Н.1, КОМЗИН Д.В.2, РОГОВСКИХ В.Ю.2, ЛОКТИН Е.М.2, ШМАКОВ А.Н.1,ФЛЯГИН Т.С.2 1 Новосибирский Государственный Медицинский Университет
2 МБУЗ НСО Городская Клиническая Больница № 2
ВЕСТНИК НОВЫХ МЕДИЦИНСКИХ ТЕХНОЛОГИЙ
Том: 24, Номер: 1 Год: 2017 Страницы: 103-108
УДК: 616.831-005-036.11-053.9:616-039.72
Новый высокочувствительный и высокоспецифичный маркер неонатального сепсиса - пресепсин
Д.Ж. БАТЫРБАЕВА, Б.А. РАМАЗАНОВА, А. БЕКНАЗАРОВА, Ж.С. АЛИБАЕВА, А.А. АБДРАИМОВАА.Д. НУРАХОВА, Н.К. ИБРАЕВА, Р.С. БАТЫРХАНОВА
Казахский Национальный медицинский университет им. С.Д. Асфендиярова, НИИ ПФМ им. Б.А. Атшабарова,
Научная клинико-диагностическая лаборатория
Comparison of qSOFA (quick SOFA) Score, Presepsin, Procalcitonin and Lactate for Severity Assessment and Mortality Prediction in Patients with Initial Sepsis
E. Spanuth1, H. Ebelt2, B. Ivandic3, R. Thomae4, K. Werdan2. 1DIAneering - Diagnostics Engineering & Research,Heidelberg, Germany, 2Department of Medicine III, University Clinics Halle (Saale), Martin-Luther- University Halle-Wittenberg,
Halle, Germany, 3Department of Medicine III, University of Heidelberg; DIAneering
– Diagnostics Engineering & Research, Heidelberg, Germany, 4Mitsubishi Chemical Europe, Düsseldorf, Germany
Presepsin is a potent biomarker for diagnosing skin wound infection in hemodialysis patients compared to white blood cell count, high-sensitivity C-reactive protein, procalcitonin, and soluble CD14
Jun Shiota1,2*, Hitoshi Tagawa2, Norihiko Ohura3 and Hitoshi Kasahara2* Correspondence: jun.siota@grp.zenjinkai.or.jp
1Department of Internal Medicine, Tsunashima Kidney Clinic, 1-10-4
Tsunashima-Higashi, Kohoku-ku, Yokohama 223-0052, Japan
2Department of Internal Medicine, Kichijoji Asahi Hospital, Tokyo, Japan
Diagnostic Accuracy of Presepsin (sCD14-ST) for Prediction of Bacterial Infection in Cerebrospinal Fluid Samples from Children with Suspected Bacterial Meningitis or Ventriculitis
David Stubljar,a Andreja Natasa Kopitar,a Mojca Groselj-Grenc,b Kristina Suhadolc,c Teja Fabjan,c Miha SkvarcaInstitute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Sloveniaa; Department of Paediatric Surgery and Intensive Care,
University Medical Centre Ljubljana, Ljubljana, Sloveniab; Clinical Institute of Clinical Chemistry and Biochemistry, University Medical Centre Ljubljana, Ljubljana, Sloveniac
Comparison of lactate, presepsin and procalcitonin with the new Qsofa (quick sofa) score for severity assessment and mortality Prediction in patients with initial sepsis
E. Spanuth 3, H. Ebelt 1, B. Ivandic 2, R. Thomae 4, K. Werdan 11Department of Medicine III, University Clinics Halle (Saale), Martin-Luther-University Halle- Wittenberg, Germany
2Department of Medicine III, University of Heidelberg, Heidelberg, Germany; DIAneering – Diagnostics Engineering & Research
GmbH, Heidelberg, Germany
3DIAneering – Diagnostics Engineering & Research GmbH, Heidelberg, Germany
4Mitsubishi Chemical Europe, Düsseldorf, Germany
Presepsin levels in cirrhotic patients with bacterial infections presented with or without acute kidney injury
Ioannis Elefsiniotis¹, Stefanos Α. Tsakiris¹, Georgia Barla¹, Eftychia Evangelidou¹, DimitriosVrachatis¹, Christos Mavrogiannis¹ ¹Academic Department of Internal Medicine-Hepatogastroenterology, General and Oncology
Hospital of Kifisia "Agioi Anargyroi", National and Kapodistrian University of Athens, Greece
FRI-018 Presepsin (soluble CD14 subtype) levels in cirrhotic patients with bacterial infections and/or portal hypertension related bleeding presented with or without acute kidney injury
I.S. Elefsiniotis1 , S. Tsakiris1 , G. Barla1 , A. Tasovasili1 , I. Stathopoulou1 ,K. Tampouratzi1 , E. , Evangelidou1 , D. Vrachatis1 , C. Mavrogiannis1 .
1 Internal Medicine-Hepatogastroenterology, General and Oncology Hospital of Kifisia “Agioi Anargyroi”,
National and Kapodistrian University of Athens, Athens, Greece E-mail: ielefs@nurs.uoa.gr
Utility of presepsin and procalcitonin for infection diagnosis during Acute necrotizing pancreatitis
Igor Khomiak*2, Oleksandr Rotar1,2, Gregory Petrovsky3, Mikhail Nazarchuk3, Vasyl Rotar1, Andrii Khomiak21General Surgery, Bukovinian State Medical University, Chernivtsi, Ukraine; 2Department of Pancreas Surgery
and Bile Ducts Reconstruction Surgery, A. A.Shalimov National Institute of Surgery and Transplantology, Kyiv,
Ukraine; 35th City Hospital, Minsk, Belarus
The clinical significance of sCD14-ST for blood biomarker in neonatal hematosepsis
Ting Xiao, Master’s Degreea, Li-Ping Chen, Master’s Degreea, Li-hua Zhang, Bachelor’s Degreeb,Fu-Huang Lai, Bachelor’s Degreeb, Li Zhang, Bachelor’s Degreeb, Qun-feng Qiu, Bachelor’s Degreea,
Rong-Liang Que, Bachelor’s Degreea, SiSi Xie, Master’s Degreea, Ding-Chang Wu, Bachelor’s Degreea,∗
The Level of Oxidative Neutrophil Response When Determining Endotoxin Activity Assay: A New Biomarker for Defining the Indications and Effectiveness of Intensive Care in Patients with Sepsis
Michael Yaroustovsky, Ekaterina Rogalskaya, Marina Plyushch,Ludmila Klimovich, Nataliya Samsonova, and Marina Abramyan
Federal State Budget Institution “Bakulev National Scientific and Practical Center for Cardiovascular Surgery” of the Ministry of Healthcare of the Russian Federation (Bakulev NSPCCS), Moscow, Russia
Диагностическое и прогностическое значение современных биохимических маркеров септических осложнений у больных после операций на сердце и сосудах
Рогальская Екатерина АнатольевнаАВТОРЕФЕРАТ
диссертации на соискание ученой степени кандидата медицинских наук
Москва – 2017
Диссертационная работа выполнена в Федеральном государственном бюджетном учреждении «Национальный научно-практический центр сердечно-сосудистой хирургии имени А.Н. Бакулева» Министерства здравоохранения Российской Федерации
Научные руководители:
Доктор медицинских наук, профессор, член-корр. РАН Ярустовский Михаил Борисович
Доктор медицинских наук, профессор Самсонова Наталия Николаевна
Role of presepsin compared to C-reactive protein in sepsis diagnosis and prognostication
Mohamed El-Saied El-Shafie a, Khaled M. Taema a,⇑, Moataz M. El-Hallag a,Abdallah Mohamed Abdallah Kandeel b
a Critical Care Medicine, Cairo University, Egypt
b Critical Care Medicine, El-Sahel Teaching Hospital, Egypt
Биологические маркеры в диагностике и лечении сепсиса (обзор литературы)
А. А. Звягин, В. С. Демидова, Г. В. СмирновФГБУ «Институт хирургии им. А. В. Вишневского» Минздрава России; Россия, 117997, Москва, ул. Большая Серпуховская, 27
Контакты: Альфред Аркадьевич Звягин zvyagin@ixv.ru
Plasma presepsin level is an early diagnostic marker of severe febrile neutropenia in hematologic malignancy patients
Yusuke Koizumi1,2*, Kaoru Shimizu3, Masayo Shigeta3, Takafumi Okuno2, Hitoshi Minamiguchi2, Katsuyuki Kito2,Keiko Hodohara2, Yuka Yamagishi1, Akira Andoh2, Yoshihide Fujiyama2 and Hiroshige Mikamo1
1Department of Clinical Infectious Diseases, Aichi Medical University, 1-1
Yazakokarimata, Nagakute, Aichi 480-1195, Japan
2Department of Gastroenterology and Hematology, Shiga University of Medical Science, Otsu 520-2192, Japan
Presepsin and Inflammatory Markers Correlate with Non-occlusive Mesenteric Ischemia after Cardiovascular Surgery
Jonas Stroeder, MD, Homburg, Germany (Presenter) Nothing to DiscloseHeinrich Groesdonk, Homburg, Germany (Abstract Co-Author) Nothing to Disclose
Hans-Joachim Schaefers, MD, Homburg, Germany (Abstract Co-Author) Nothing to Disclose
Matthias Klingele, Homburg, Germany (Abstract Co-Author) Nothing to Disclose
Stefan Wagenpfeil, Homburg, Germany (Abstract Co-Author) Nothing to Disclose
Marcus Katoh, MD, Krefeld, Germany (Abstract Co-Author) Consultant, Straub Medical AG Consultant, Medtronic, Inc
Hagen Bomberg, Homburg, Germany (Abstract Co-Author) Nothing to Disclose
Arno Buecker, MD, Homburg, Germany (Abstract Co-Author) Research Grant, Siemens AG; Consultant, Bracco Group; Speaker,
Peter Minko, MD, Homburg, Germany (Abstract Co-Author) Speaker, Straub Medical AG Consultant,
Straub Medical AG
Diagnostic and Prognostic Value of Presepsin for Subclinical Chorioamnionitis in Pregnancies between 23-28 Week with Preterm Premature Rupture of the Membranes
Erbil Çakar¹, Şule Eren Çakar², Habibe Ayvacı Taşan¹, Deniz Karçaaltıncaba³, Mehmet Baki Şentürk¹,Nermin Koç4, Ramazan Uluhan5
¹Department of Obstetrics and Gynecology, Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital, İstanbul, Turkey
²Deparment of Infectious Diseases, Ümraniye Training and Research Hospital, İstanbul, Turkey
³Department of Obstetrics and Gynecology, Gazi University School of Medicine, Ankara, Turkey
4Department of Pathology, Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital, İstanbul, Turkey
5Department of Clinical Microbiology, Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital, İstanbul, Turkey
The Results of the Russian Clinical Trial of Mesenchymal Stromal Cells (MSCs) in Severe Neutropenic Patients (pts) with Septic Shock (SS) (RUMCESS trial)
Gennadii M. Galstian, Elena N. Parovichnikova, Polina M. Makarova, Larisa A. Kuzmina,Vera V. Troitskaya, Eduard Gemdzhian, Nina I. Drize and Valeri G. Savchenko
Blood 2015 126:2220; http://www.bloodjournal.org/content/126/23/2220?sso-checked=true
Presepsin (soluble CD14 subtype) Is Available in Febrile Neutropenic Patients with Hematological Malignancy As Diagnosis and Assesment Biomarker of Infections
Tatsuo Oyake, Takayuki Masuda, Norifumi Sugawara, Maki Asahi, Yuzo Suzuki, Yoshiaki Okano, Yukiteru Fujishima, Yusei Aoki, Shugo Kowata, Shigeki Ito and YojiIshida
Presepsin in Early Laboratory Diagnostics and Monitoring of Sepsis in Pediatric Patients with Oncology Diseases
Golovnya E., Baykova V., Saltanov A., Sotnikov A.Institute of Pediatric Oncology and Hematology of Federal State N. N. Blokhin Russian Cancer Research Center, Moscow
3rd international Presepsin workshop,
Rome, September 17, 2016
Plasma Levels of Presepsin (Soluble CD14-subtype) as a Novel Prognostic Marker for Hemophagocytic Syndrome in Hematological Malignancies
Satoru Nanno1, Hideo Koh1, Takako Katayama 1, Masamichi Hashiba 2, Ayumi Sato 2,Yosuke Makuuchi1, Joji Nagasaki 1, Masatomo Kuno1, Takuro Yoshimura 1, Hiroshi Okamura1,
Mitsutaka Nishimoto 1, Asao Hirose 1, Mika Nakamae1, Takahiko Nakane 1,
Masayuki Hino1 and Hirohisa Nakamae1
Diagnostic value of sepsis biomarkers in hematopoietic stem cell transplant recipients in a condition of high prevalence of gram-negative pathogens
Igor Stoma a,* , Igor Karpov a , Anatoly Uss b , Oleg Rummo b ,Natalia Milanovich b , Igor Iskrov b
a Department of Infectious Diseases, Belarusian State Medical University, Minsk, Belarus
b City Clinical Hospital No. 9, Minsk, Belarus
Прeсепсин пригоден для ранней диагностики сепсиса согласно новому международному определению СЕПСИС-3
EuSEM congress,Vienna, 2-5 October, 2016.AbstractsTomonori YAMAMOTO, Yamamoto HIROMASA, Tetsuro Nishimura TETSURO,
Shinyama NAOKI, Noda TOMOHIRO, Shinichiro KAGA, Takahumi TERADA,
Kenichiro UCHIDA, Takasei MORIOKA, Hiroharu TAKESADA, Maiko ESAKI, Hoshi
HIMURA, Yasumitsu MIZOBATA
Пресепсин – ранний и надежный диагностический и прогностический маркер неонатального сепсиса
Jehan H Sabry1, Osama A Elfeky2, Akram E Elsadek3, Ahmed A Eldaly4.1. Assistant Professor of Clinical & Chemical Pathology, Benha Faculty of Medicine, Egypt.
2. Professor of Pediatrics, Benha Faculty of Medicine, Egypt.
3. Lecturer of Pediatric, Benha Faculty of Medicine, Egypt.
4. Resident of Pediatrics, Ministry of Health, Egypt.
Plasma Levels of Presepsin (Soluble CD14-subtype) as a Novel Prognostic Marker for Hemophagocytic Syndrome in Hematological Malignancies
Satoru Nanno1, Hideo Koh1, Takako Katayama 1, Masamichi Hashiba 2, Ayumi Sato 2,Yosuke Makuuchi1, Joji Nagasaki 1, Masatomo Kuno1, Takuro Yoshimura 1, Hiroshi Okamura1,
Mitsutaka Nishimoto 1, Asao Hirose 1, Mika Nakamae1, Takahiko Nakane 1,
Masayuki Hino1 and Hirohisa Nakamae1
Пресепсин как маркер краткосрочной динамики состояния у пациентов с внутрибольничной инфекцией
Справочник заведующего КДЛ, 2016, N7Л.Б. Гайковая, д-р мед. наук, заведующая центральной клинико-диагностической лабораторией, заведующая кафедрой биологической и общей химии,
К.А. Загородникова, канд. мед. наук, доцент кафедры терапии и клинической фармакологии
А.И. Ермаков, врач клинической лабораторной диагностики центральной клинико-диагностической лаборатории
А.С. Федоренко, канд. мед. наук, врач – клинический фармаколог
М.А. Костицына, врач – клинический фармаколог
М.В. Покладова, врач – клинический фармаколог
А.Т. Бурбелло, д-р мед. наук, проф., врач – клинический фармаколог
ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России, г. Санкт-Петербург
The role of Presepsin (sCD14-ST) as an indirect marker of microbial translocation and immune activation in HIV and HIV/HCV coinfected patients
V. Zuccaro (1), P. Sacchi (1), S. Cima (1), P. Columpsi (1), S. Toppino (1), S. Paolucci (2), G. Comolli (2), F. Baldanti (2), M. Mariconti (1), R. Bruno (1)1) Dipartimento di Malattie Infettive, Fondazione IRCCS Policlinico San Matteo, Pavia .
2) Unità di Virologia Molecolare, S.C. di Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia
Diagnostic and prognostic value of soluble CD14 subtype (Presepsin) for sepsis and community‑acquired pneumonia in ICU patients
Kada Klouche1,2* , Jean Paul Cristol2,3, Julie Devin3, Vincent Gilles1, Nils Kuster3, Romaric Larcher1,Laurent Amigues1, Philippe Corne1, Olivier Jonquet1 and Anne Marie Dupuy3
Presepsin as an important diagnostic biomarker that differentiates sepsis from non-infectious SIRS in critical ill adult patients: A system review and meta-analysis
Dan Xie1 †, Kunpeng Hu2 †, Purun Lei3, Ying Xian1, Ying Wang1, Xiaogang Bi1, Kouxing Zhang1**Correspondence: Professor Kouxing Zhang, Department of General ICU of Lingnan Hospital, The Third Affiliated Hospital, Sun Yat-sen
University, Guangzhou, China,
Применение пресепсина и прокальцитонина в диагностике сепсиса у тяжело обожженных пациентов
Жилинский Е.В.1, Алексеев С.А. 2, Жензерова И.А. 1, Блыга Е.Г. 1УЗ «Городская клиническая больница скорой медицинской помощи», Минск, Беларусь
УО «Белорусский государственный медицинский университет», Минск, Беларусь
Role of Presepsin for the Assessment of Acute Cholangitis Severity
Jianbo Lin1, Huidong Sun2, Jiangong Li1, Yanhong Zheng1, Cunhua Shao1, Yang Zhang1, Hong Chang31 Department of Hepatobiliary Surgery, Shandong Provincial Hospital (group) Dongying Hospital Affiliated to Shandong University, Dongying
People’s Hospital, Dongying, Shandong, China 2 Department of Hepatobiliary Surgery, The People's Hospital of Liaocheng, Liaocheng,
Shandong, China 3 Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China
Использование пресепсина (sCD14-ST) в качестве маркера сепсиса при критических состояниях
Е.Г. Головня, А.И. Салтанов, А.В. Сотников, В.Н. БайковаНаучно-исследовательский институт детской онкологии и гематологии Российского онкологического
научного центра им. Н.Н. Блохина Минздрава России, Москва, Российская Федерация
Presepsin (Soluble CD14 Subtype): Reference Ranges of a New Sepsis Marker in Term and Preterm Neonates
Lorenza Pugni1*, Carlo Pietrasanta1, Silvano Milani2, Claudia Vener2, Andrea Ronchi1,Mariella Falbo1, Milena Arghittu3, Fabio Mosca1
1 NICU, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca’ Granda Ospedale
Maggiore Policlinico, University of Milan, Milan, Italy, 2 Laboratory “GA Maccacaro”, Department of Clinical
Sciences and Community Health, University of Milan, Milan, Italy, 3 Microbiology Laboratory, Fondazione
IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
Biomarkers and empiric antibiotic therapy appropriateness in critically ill septic patients: role of presepsin
R. Renna, S. Cassano, A. Sicolo, G. Lupo, M.J. Mura Ondok, G. Altamura,L. Dalfino, F. Bruno, N. Brienza
Anesthesia and Intensive Care Unit, Department of Emergency and Organ
Transplantation, University Aldo Moro of Bari, Bari, Italy
Presepsin and procalcitonin for sepsis diagnosis and appropriateness of antibiotic therapy prediction in critically ill patients
F. Di Serio1, L. Varraso1, L. Dalfino2, S. Cassano2, R.G. Renna2, F. Bruno21Clinical Pathologist Unit, University-Hospital Bari, Bari
2Anesthesia and Intensive Care Unit, University-Hospital Bari, Bari
Presepsin as a new biomarker for old expectations in the diagnosis and prognosis of bacterial infection in cirrhosis
Maria Papp*, Tamas Tornai1, David Tornai2, Zsuzsanna Vitalis1, Istvan Tornai1,Peter Antal-Szalmas2
1Gastroenterology, 2Laboratory Medicine, University of Debrecen, Debrecen, Hungary
Corresponding author’s e-mail: drpappm@yahoo.com
Soluble CD14-subtype (Prespsin) and Hepcidin as Diagnostic and Prognostic markers in Early Onset Neonatal Sepsis
1Tawfik Abdel Motalib*, 2Fatma A Khalaf , 3Ghada El Hendawy,4Sobhy E Kotb, 5Aml M Ali, 6Amal El Sharnoby
Departments of 1Microbiology, 2Clinical Biochemistry & 6Clinical Pathology, National Liver Institute, Menoufiya
University; 3Microbiology Department, Faculty of Medicine - Menoufiya University; Departments of Pediatric,
4Dubai Hospital & 5Ahmed Maher Teaching Hospital
Применение мультипотентных мезенхимных стромальных клеток для лечения септического шока у больных в состоянии агранулоцитоза.
Макарова Полина МихайловнаФедеральное государственное бюджетное учреждение
Гематологический научный центр
Министерства здравоохранения Российской Федерации
На правах рукописи
Diagnostic and prognostic utility of soluble CD 14 subtype (presepsin) for severe sepsis and septic shock during the first week of intensive care treatment
Michael Behnes1, Thomas Bertsch2, Dominic Lepiorz1, Siegfried Lang1, Frederik Trinkmann1, Martina Brueckmann3,Martin Borggrefe1 and Ursula Hoffmann1*
The False Positive Soluble CD 14 Subtype is Lower Than That of Procalcitonin in Postoperative Severe Elective Surgery Patients: A Prospective Observational Trial
Yoshitaka Hara, M.D., Tomoyuki Nakamura, M.D., Naohide Kuriyama, M.D.,Satoshi Komatsu, M.D., Seiko Hayakawa, M.D., Sohta Uchiyama, M.D.,
Daisuke Niimi, M.D., Chizuru Yamashita, M.D., Junpei Shibata, M.D.,
Ph.D., Osamu Nishida, M.D.,Ph.D.
Fujita Health University School of Medicine, Toyoake, Japan
Вазоактивный эффект ропивокаина при блокаде седалищного нерва у больных с диабетической стопой
Т. С. Флягин1, В. Н. Кохно2, Е. М. Локтин11ГБУЗ НСО «Городская клиническая больница № 2» (г. Новосибирск)
2ГБОУ ВПО «Новосибирский государственный медицинский университет» Минздрава
России (г. Новосибирск)
Динамика пресепсина и прокальцитонина у пациентов хирургического профиля
Кулабухов В.В., Демидова В.С., Кудрявцев А.Н., Чижов А.Г., Звягин А.А.,Терехова Р.П., Баранова А.А.
ФГБУ «Институт хирургии им. А.В.Вишневского» Минздрава России
Тезисы XII Съезда хирургов России 5-10 октября 2015 г. г. Ростов-на-Дону
Usefulness of Presepsin (sCD14-ST) in diagnosis of Infective Endocarditis - preliminary results of an observational study
Adriana Topan1, Dumitru Carstina1, Raluca Rancea2, Adriana Slavovici1, MirelaFlonta3, Mihaela Lupse1
1. University of Medicine and Pharmacy”Iuliu Hatieganu”, Cluj-Napoca; 2. Institut of the Heart
“Nicolae Stancioiu” , Cluj – Napoca; 3. Hospital of Infectious Diseases, Cluj- Napoca, Romania
Monitoring of weaning from mechanical ventilation in Critical ill patients by pathfast presepsin at the intensive care unit
E. Spanuth 2, R. Thomae 3, E. Giannitsis 11Deptartment of Medicine III, Div. of Cardiology, University of Heidelberg, Heidelberg, Germany
2DIAneering - Diagnostics Engineering & Research, Heidelberg, Germany
3Misubishi Chemical Europe, Düsseldorf, Germany
Presepsin can replace procalcitonin in the prediction of sepsis In transplant patients after antithymocyte globulin administration
E. Spanuth1, B. Ivandic1, J. Wilhelm3, R. Thomae2, K. Werdan31DIAneering - Diagnostics Engineering & Research, Heidelberg, Germany
2Mitsubishi Chemical Europe, Düsseldorf, Germany
3University Clinics Halle (Saale), Department of Medicine III, Martin-Luther-University
Halle-Wittenberg, Germany
Prognostic significance of presepsin in patients with sepsis
E. Rogalskaya3, M. Plyushsh2, N. Samsonova3, M. Yaroustovsky11Department of Detoxication and Endoscopy, Bakoulev Scientific Center for Cardiovascular Surgery, Moscow
2Laboratory of Biochemistry, Clinical Laboratory Diagnostics Division, Bakoulev Scientific Center for Cardiovascular Surgery, Moscow
3Laboratory of Hematology, Clinical Laboratory Diagnostics Division, Bakoulev Scientific Center for Cardiovascular Surgery, Moscow
Clinical Impact of Kidney Function on Presepsin Levels
Takanobu Nagata1, Yoshinari Yasuda1, Masahiko Ando2, Tomoko Abe1,Takayuki Katsuno1, Sawako Kato1, Naotake Tsuboi1, Seiichi Matsuo1,
Shoichi Maruyama1*
1 Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan, 2 Center for
Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan
Combined assessment of presepsin (scd14-st) and mortality in Emergency department sepsis (meds) score improves outcome prediction of sepsis
E. Spanuth1, B. Ivandic1, J. Wilhelm3, R. Thomae2, K. Werdan31DIAneering - Diagnostics Engineering & Research, Heidelberg, Germany
2Mitsubishi Chemical Europe, Düsseldorf, Germany
3University Clinics Halle (Saale), Department of Medicine III, Martin-Luther-University
Halle-Wittenberg, Germany
Перспективы применения новых лабораторных методов в ранней диагностике сепсиса
Годило-Годлевский В.А., полковник вн. сл. в отставке, заместитель главного врача Медико-реабилитационного центра «Здоровье для вас», доцент кафедры факультативной терапии и пропедевтики внутренних болезней Государственной классической академии им. Маймонида, д.м.н., vg-god@rambler.ruГурбатова Т.Ю., начальник лабораторного отделения Главного клинического госпиталя МВД России;
Мельникова С.В., подполковник вн. сл., заместитель начальника лабораторного отделения – врач клинической лабораторной диагностики Главного клинического госпиталя МВД России, к.б.н.
Пресепсин в диагностике гнойных осложнений у хирургических больных и пациентов с ожоговой травмой
Демидова В.С., Ушакова Т.А., Звягин А.А., Бобровников А.Э., Медова О.В., КоряковИ.А., Казеннов В. В., Шишкин М.Н., Баранова А.А., Самадурова Л.Л., Кучейник А.Ш.
ФГБУ «Институт хирургии им. А.В. Вишневского», Россия, Москва
Diagnostic Value of Presepsin (Scd14-St Subtype) Evaluation in the Detection of Severe Neonatal Infections
Stojewska Małgorzata Department of Pediatrics Zabrze, Silesian Medical University Katowice, PolandBehrendt Jakub, Szymańska Anna, Pukas-Bochenek Anna, Stachurska Aneta, Godula – Stuglik Urszula Department of Neonatal Intensive Care Units Zabrze, Silesian Medical University Katowice, Poland
Mazur Bogdan Depatrment of Microbiology and Immunology Zabrze, Silesian Medical University Katowice, Poland
Presepsin: A Novel and Potential Diagnostic Biomarker for Sepsis
K V Ramana1,*, Venkata BharatKumar Pinnelli2, Sabitha Kandi3, Asha G2, Jayashankar CA4, Bhanuprakash5, Raghavendra DS2, Sanjeev D rao11Department of Microbiology, Prathima Institute of Medical sciences, Karimnagar, India 2Department of Biochemistry, Vydehi Institute of Medical sciences and Research center, Bengaluru, India 3Department of Biochemistry, Chalmeda Anandarao Institute of Medical sciences, Karimnagar, India 4Department of General Medicine, Vydehi Institute of Medical sciences and Research center, Bengaluru, India 5Department of Dermatology, Vydehi Institute of Medical sciences and Research center, Bengaluru, India
*Corresponding author: ramana_20021@rediffmail.com
Diagnostic and prognostic performance of PATHFAST Presepsin in patients with SIRS and early sepsis
E Spanuth1, R Carpio2, R Thomae31DIAneering GmbH, Heidelberg, Germany; 2Hospital Nacional Edgardo
Rebagliati Martins-EsSalud, Lima, Peru; 3Mitsubishi Chemical Europe,
Dьsseldorf, Germany
Critical Care 2015, 19(Suppl 1):P63 (doi: 10.1186/cc14143)
Determination of reference interval for presepsin, an early marker for sepsis
Davide Giavarina, Mariarosa Carta. Determination of reference interval for presepsin, an early marker for sepsis. Biochemia Medica 2015;25(1):64-8. http://dx.doi.org/10.11613/BM.2015.007 Clinical Chemistry and Haematology Laboratory, San Bortolo Hospital, Vicenza, ItalyPresepsin (soluble CD14 subtype) in term and preterm newborns
Lorenza Pugni1, Carlo Pietrasanta1, Mariella Falbo1, Tania Todorovic1, Claudia Vener2, SilvanoMilani2, Fabio Mosca1
1NICU, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca’ Granda
Ospedale Maggiore Policlinico, University of Milan, Milan, Italy 2Medical Statistics and
Biometrics Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Ca’
Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
Early Human Development, Volume 90, Supplement 2, Pages S64–S65, September 2014
The clinical performance of a point of care assay for measurement of Presepsin in patients with bacteremia
Yasuo Fukui 1) Yoshikazu Okamura 2)•1) Department of Gastroenterological Surgery, Kochi Health Sciences Center, Kochi, Japan
•2) Research and Development Division, Yachiyo R&D Department, Mitsubishi Chemical Medience Corporation,Tokyo, Japan
Serum prepsepsin (soluble cd14-subtype) as a novel useful biomaker for infection in patients with rheumatoid arthritis (ra)
S. Tsuji1, S. Ohshima2, A. Yura3, M. Katayama1, A. Watanabe1, S. Teshigawara1, M. Yoshimura1, E. <br>Tanaka1, Y. Harada3, Y. Katada3, M. Matsushita1, A. Taura2, A. Kitatoube2, G. Takahashi4, S. Endo4,<br>
J. Hashimoto1, Y. Saeki2.<br>
1 Rheumatology; 2 Clinical Research; 3Allergology, National Hospital Organization Osaka Minami Medical Center, Kawachinagano<br>
Osaka; 4Critical Care Medicine,<br>
Iwate Medical University, Uchimaru, Morioka, Japan
Diagnostic and prognostic value of presepsin in preterm deliveries
Abstracts / Journal of Reproductive Immunology 101–102 (2014) 40–60Karin Malícˇková1,∗, Michal Koucky´ 2, Antonín Parˇízek2,
Kvˇeta Pelinková1, Helena Brodská1, Zdenˇek Hájek2, Anna
Germanová2, Oto Mestek3, Tomáˇs Zima1
1 Institute of Medical Biochemistry and Laboratory Diagnostics,
General University Hospital and 1st Faculty of Medicine
of Charles University in Prague, Czech Republic
2 Department of Gynecology and Obstetrics, General University
Hospital and 1st Faculty of Medicine of Charles University
in Prague, Czech Republic
3 Institute of Chemical Technology Prague, Czech Republic
Diagnostic and Predictive Value of Presepsin (sCD14-ST) in the Time Course of Sepsis
Michael Behnes¹, Dominic Lepiorz ¹, Siegfried Lang¹, Thorsten Kälsch¹, <br>Thomas Bertsch², Martina Brueckmann¹*, Martin Borggrefe¹, Ursula Hoffmann¹<br>
First Department of Medicine¹, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, Germany<br>
Institute for Clinical Chemistry, Laboratory and Transfusion Medicine², Nuremberg Hospital, Germany
Assessment of the usefulness of Presepsin (soluble CD14 subtype; sCD14-ST) in septic patients
Takeshi Nishida1, Hiroyasu Ishikura1, Akira Murai1, Yuhei Irie1, Takehiro Umemura1, Takanori Kamitani1, Shigeatsu Endo2, The Presepsin Workshop1 Department of Emergency and Critical Care Medicine, Fukuoka University Hospital, Fukuoka, JAPAN
2 Department of Critical Care Medicine, School of Medicine, Iwate Medical University, Iwate, JAPAN
Presepsin (soluble CD14 subtype) Is Secreted from Human Monocytes after Phagocytosis
Yasuyuki Arai, MD1, Kouhei Yamashita, MD, PhD1, Kiyomi Mizugishi,MD, PhD1 and Akifumi Takaori-Kondo, M.D., Ph.D.2
Department of Hematology and Oncology, Kyoto University Graduate
School of Medicine, Kyoto, Japan
Department of Hematology and Oncology, Graduate School of Medicine,
Kyoto University, Kyoto, Japan
Diagnostic value of presepsin in cirrhotic patients
G. Novelli1, V. Morabito1, G. Ferretti2, N. Gugliemo1, G.B. Levi Sandri1, M. Rossi1, P.B. Berloco1.1General Surgery and Organs Transplant, 2Tropical and Infectous Disease, Sapienza University, Rome, Italy
Journal of Hepatology Volume 58, Supplement 1 , Pages S95-S96, April 2013
Diagnostic and prognostic value of serum presepsin in cirrhotic patients with spontaneous bacterial peritonitis
H. Okasha1, A. Elgohary2, A. Abd El Moety2, A. Elbadawy3Medical microbiology and Immunology, Faculty of medicine Alexandria university, Alexandria, Egypt;
Internal Medicine, Faculty of medicine Alexandria university, Alexandria, Egypt ; Internal Medicine,
Alexandria Police Hospital, Alexandria, Egypt
Prognostic value of presepsin (soluble cd14 subtype) in critically ill patients with severe sepsis and septic shock
AbdAllah T.H. 1, El-Reweny E.M.1, El-Sawy M.M.2, Aboudeif M.M.11Department of Critical Care Medicine, Faculty of Medicine, Alexandria University, Egypt 2Department of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Egypt
Диагностическое и прогностическое значение пресепсина при септическом шоке у онкогематологических больных в состоянии агранулоцитоза. Статья.
Макарова П.М., Галстян Г.М., Кречетова А.В., Гаранжа Т.А.,Тихомиров Д.С., Паровичникова Е.Н.
ФГБУ «Гематологический научный центр» Минздрава России,
г. Москва
Роль продленной вено-венозной гемофильтрации в коррекции липополисахаридемии и ассоциированных с ней маркеров грамотрицательного сепсиса
Р.М. Зайцев, А.Ю. Яковлев, А.В. Абрамов, С.Ю. Власкин,М.Ю. Серопян, А.А. Ниязматов, А.Ю. Сморкалов, Е.Ю. Голубцова
ГБУЗ НО «Нижегородская областная клиническая больница им. Н.А. Семашко»
Диагностическое и прогностическое значение пресепсина при септическом шоке у онкогематологических больных в состоянии агранулоцитоза
ФГБУ "Гематологический Научный Центр" Минздрава России. Отделение Реаниматологии и Интенсивной Терапии.П.М. Макарова, Г.М. Галстян, А.В. Кречетова, Т.А. Гаранжа, Д.С. Тихомиров, Е.Н. Паровичникова
Presepsin (soluble CD14 subtype) and procalcitonin levels for mortality prediction in sepsis: data from the Albumin Italian Outcome Sepsis trial
Serge Masson, Pietro Caironi, Eberhard Spanuth, Ralf Thomae, Mauro Panigada, Gabriela Sangiorgi,Roberto Fumagalli, Tommaso Mauri, Stefano Isgrò, Caterina Fanizza, Marilena Romero, Gianni Tognoni,
Roberto Latini, and Luciano Gattinoni, on behalf of the ALBIOS Study Investigators
Masson et al. Critical Care 2014, 18:R6
Diagnostic and prognostic value of presepsin in the management of sepsis in the emergency department: a multicenter prospective study
Marco Ulla, Elisa Pizzolato, Manuela Lucchiari, Maria Loiacono, Flavia Soardo, Daniela Forno,Fulvio Morello, Enrico Lupia, Corrado Moiraghi, Giulio Mengozzi and Stefania Battista
Ulla et al. Critical Care 2013, 17:R168