Soluble CD14 Subtype in Peripheral Blood is a Biomarker for Early Diagnosis of Sepsis

Objective: To study the value of serum soluble CD14 subtype (sCD14-ST) in early diagnosis of sepsis.

Methods: Seventy-two patients were diagnosed with systemic inflammatory response syndrome, sepsis, or septic shock. Peripheral blood was collected at 0, 12, 24, and 48 hours after admission to the hospital. Levels of sCD14-ST, procalcitonin (PCT), hypersensitive C-reactive protein (CRP), and white blood cells (WBC) were determined.