Comparison of lactate, presepsin and procalcitonin with the new Qsofa (quick sofa) score for severity assessment and mortality Prediction in patients with initial sepsis

Background: The SOFA score is associated with an increased probability of mortality in sepsis. For assessment at admission in the ED several laboratory variables are necessary. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined a new qSOFA score, which does not require laboratory tests and can be easily assessed at patient admission.
Objective: To compare established sepsis biomarkers with SOFA and qSOFA to discriminate uncomplicated sepsis, severe sepsis or septic shock and to evaluate the association with poor outcome and increased risk of mortality.