Presepsin as a Biomarker for Sepsis Evolutions in Diabetis

The sepsis represents a systemic inflammatory response syndrome caused by severe infection. Sepsis causes millions of deaths globally each year.The criteria according to the systemic inflammatory response syndrome (SIRS) represents a clinical expression of the host response to inflammation and beeing described 24 years ago. This approach was codified by the consensus statement of the American College of Chest Physicians and Society of Critical Care Medicine in 1993 and has been the predominant approach to classifying sepsis. As a costly disease, sepsis not only lowers patient’s living quality, but also increases the mortality[1-4]. Early diagnosis in sepsis is imperative to save patient life. Sensitive biomarkers are required for early diagnosis and as indexes of prognosis sepsis.