Diagnostic value of presepsin in cirrhotic patients

Introduction: The natural course of chronic liver disease is often complicated by acute episodes of potentially reversible decompensation, triggered by a precipitating event such as an infection. Presepsin (sCD14) has been identified as a protein whose levels increase specifically in the blood of patients with bacterial infection. Pathfast Assay System (PAS) is able to detect the levels of sCD14. In this study, we evaluated the clinical performance of PAS and its usefulness in the early diagnosis of bacterial infection in cirrhotic patients.